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Lung Cancer clinical trials in Greenville, SC

9 studies for Lung Cancer are looking for participants at sites in and around Greenville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Saint Francis Hospital, Greenville
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Greenville Memorial Hospital, Greenville
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Cancer Institute - Eastside, Greenville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Prisma Health Cancer Institute, Greenville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Saint Francis Hospital, Greenville
  • Saint Francis Cancer Center, Greenville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Greenville Memorial Hospital, Greenville
  • and 1 more
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Cancer Institute - Eastside, Greenville
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Greenville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Greenville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.