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Lung Cancer clinical trials in Knoxville, TN

10 studies for Lung Cancer are looking for participants at sites in and around Knoxville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Tennessee Cancer Specialists Dowell Springs location, Knoxville
  • University of Tennessee Medical Center, Knoxville
  • Tennessee Cancer Specialists - Parkwest Location, Knoxville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

RecruitingPhase 2
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07489066

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

RecruitingPhase 3
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • University of Tennessee - Knoxville, Knoxville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • University of Tennessee Medical Center, Knoxville
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Knoxville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.