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COPD clinical trials in Knoxville, TN

5 studies for COPD are looking for participants at sites in and around Knoxville (within about 30 miles). Open a study to see who can join and how to contact the study team.

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

Recruiting
  • Fort Sanders Regional Medical Center (StatCare), Knoxville
Ages 40 to 80 · All sexes · Updated Sep 17, 2026 · NCT06035120

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

RecruitingPhase 3
  • Research Site, Knoxville
Ages 40 to 80 · All sexes · Updated Sep 3, 2026 · NCT06878261

Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators

RecruitingPhase 4
  • The University of Tennessee Graduate School of Medicine, Knoxville
Ages 40 and older · All sexes · Updated Aug 17, 2026 · NCT07133880

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

RecruitingPhase 3
  • GSK Investigational Site, Knoxville
Ages 40 to 75 · All sexes · Updated Jul 28, 2026 · NCT07177339

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

RecruitingPhase 3
  • GSK Investigational Site, Knoxville
Ages 40 to 80 · All sexes · Updated Apr 9, 2026 · NCT06961214

About COPD

COPD (chronic obstructive pulmonary disease) makes it hard for you to breathe. At first symptoms are mild, but they usually become more severe. Learn more.

More about COPD on MedlinePlus

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Other studies in Knoxville

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.