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Pancreatic Cancer clinical trials in Illinois

31 studies for Pancreatic Cancer are looking for participants at sites in Illinois.

Cities in Illinois

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • University of Chicago Hospital, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  • Illinois Cancer Specialists, Arlington Heights
  • City of Hope, Chicago
  • OSF Medical Center, Peoria
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

  • Northwestern University, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • University of Illinois Cancer Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

  • Northwestern Medicine Chicago Proton Center, Warrenville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT02598349

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

  • University of Chicago Medical Center, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07621718

Pancreatic Cancer Detection Consortium

  • OSF HealthCare, Peoria
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06388967

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • City of Hope Cancer Center-Chicago, Zion
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

DESTINY-PANTUMOUR04

  • Research Site, Decatur
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • Cancer Care Specialists of Illinois, Decatur
  • Decatur Memorial Hospital, Decatur
  • Hope and Healing Clinical Research LLC, Hinsdale
  • and 2 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

  • Investigative Site US079, Chicago
  • Investigative Site US030, Evanston
  • Investigative Site US005, Naperville
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

  • OSF Saint Francis Medical Center, Peoria
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

CREO - Microwave Ablation Feasibility Study

  • Rush University Medical Center, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07817147

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

  • Advocate Outpatient Center - Aurora, Aurora
  • Advocate Good Shepherd Hospital, Barrington
  • Carle BroMenn Outpatient Center, Bloomington
  • and 52 more
RecruitingObservational study
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

  • Memorial Hospital East, Shiloh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT05687123

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

  • Rush-Copley Medical Center, Aurora
  • Advocate Outpatient Center - Aurora, Aurora
  • Illinois CancerCare-Bloomington, Bloomington
  • and 45 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

  • Northwestern University, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07594626

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

  • Research Site, Chicago
RecruitingPhase 1/2
Ages 18 to 130 · All sexes · Updated Aug 12, 2026 · NCT05417594

Pancreatic Cancer Early Detection Consortium

  • Illinois CancerCare, Bloomington
  • University of Chicago Medicine, Chicago
  • NorthShore University HealthSystem, Evanston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

  • Northwestern University - Robert H. Lurie Comprehensive Cancer Center, Chicago
  • Hope and Healing Cancer Services, Hinsdale
  • Orchard Healthcare Research, Skokie
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06937177

Integrated Cancer Repository for Cancer Research

  • Rush-Copley Cancer Care Center, Aurora
  • Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

  • University of Illinois Hospital and Health Sciences System /ID# 251750, Chicago
  • University of Chicago Medical Center /ID# 276271, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT05005403

Evaluating the Prognostic Capability of ctDNA as a Biomarker in Pancreatic Cancer Patients Undergoing Neoadjuvant Chemotherapy

  • Northwestern Medicine Cancer Center Kishwaukee, DeKalb
  • Northwestern Medicine Cancer Center Delnor, Geneva
  • Northwestern Medicine Cancer Center Warrenville, Warrenville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT04616131

Lidocaine Infusion in Pancreatic Cancer

  • University of Illnois at Chicago, Chicago
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT04048278

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

  • Illinois CancerCare-Bloomington, Bloomington
  • Illinois CancerCare-Canton, Canton
  • Memorial Hospital of Carbondale, Carbondale
  • and 29 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06998940

Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

  • Northwestern University, Chicago
  • University of Illinois, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT06807437

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

  • Ohio State University-Telemedicine, Champaign
  • Ohio State University-Telemedicine, Chicago
  • Ohio State University Telemedicine, Quincy
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

  • OSF Saint Anthony's Health Center, Alton
  • Advocate Good Shepherd Hospital, Barrington
  • Illinois CancerCare-Bloomington, Bloomington
  • and 40 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source

  • Advocate Christ Medical Center, Oak Lawn
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 17, 2025 · NCT02843945

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

  • Northwestern University, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 10, 2023 · NCT05733000

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.