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Ensayos clínicos de Leucemia linfocítica crónica en Carolina del Norte

34 estudios sobre Leucemia linfocítica crónica buscan participantes en Carolina del Norte.

Ciudades en Carolina del Norte

Texto oficial del estudio (inglés)

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • Southeastern Medical Oncology Center-Goldsboro, Goldsboro
  • y 5 más
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 30 sept 2026 · NCT04269902

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

  • Research Site, Charlotte
  • Research Site, Winston-Salem
ReclutandoFase 1/2
Edades de 18 en adelante · Todos los sexos · Actualizado el 30 sept 2026 · NCT06542250

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

  • GC2202 Study Site 109, Greenville
  • GC2202 Decentralized Study Site 114, Morrisville
  • GC2202 Study Site 117, Wilson
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 30 sept 2026 · NCT05645107

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

  • University of North Carolina At Chapel Hill, Chapel Hill
  • Levine Cancer Center, Charlotte
  • Atrium Health Wake Forest Baptist, Winston-Salem
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 28 sept 2026 · NCT06943872

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

  • Atrium Health Levine Cancer Institute (Lci), Charlotte
  • Duke University Medical Center, Durham
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 28 sept 2026 · NCT07277231

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  • University of North Carolina At Chapel Hill, Chapel Hill
  • Atrium Health Levine Cancer Institute (Lci), Charlotte
  • Duke University Medical Center, Durham
  • y 1 más
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 28 sept 2026 · NCT06973187

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

  • Carolina Oncology Specialists, PA ( Site 0054), Charlotte
  • Southeastern Medical Oncology Center ( Site 0049), Goldsboro
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 24 sept 2026 · NCT06136559

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

  • Duke University, Durham
  • Novant Health Cancer Institute, Winston-Salem
ReclutandoFase 2
Edades de 18 en adelante · Todos los sexos · Actualizado el 17 sept 2026 · NCT07221500

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
ReclutandoFase 2
Edades de 18 en adelante · Todos los sexos · Actualizado el 11 sept 2026 · NCT07061951

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

  • Research Site, Charlotte
  • Research Site, Charlotte
ReclutandoFase 1/2
Edades de 18 en adelante · Todos los sexos · Actualizado el 8 sept 2026 · NCT06564038

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

  • UNC School of Medicine, Division of Hematology, Chapel Hill
ReclutandoFase 1/2
Edades de 12 en adelante · Todos los sexos · Actualizado el 3 sept 2026 · NCT04588922

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Duke University Medical Center, Durham
  • Margaret R Pardee Memorial Hospital, Hendersonville
ReclutandoFase 3
Edades de 65 en adelante · Todos los sexos · Actualizado el 2 sept 2026 · NCT07321652

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • AdventHealth Infusion Center Asheville, Asheville
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • AdventHealth Infusion Center Haywood, Clyde
  • y 6 más
ReclutandoEstudio observacionalSe aceptan voluntarios sanos
Edades de 40 a 75 · Todos los sexos · Actualizado el 2 sept 2026 · NCT05334069

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

  • Research Site, Charlotte
  • Research Site, Durham
  • Research Site, Winston-Salem
ReclutandoFase 2
Edades de 18 a 130 · Todos los sexos · Actualizado el 6 ago 2026 · NCT07024706

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

  • University of North Carolina at Chapel Hill/ University of North Carolina Medical Center, Chapel Hill
ReclutandoFase 1/2
Edades de 13 a 90 · Todos los sexos · Actualizado el 6 ago 2026 · NCT06533579

A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

  • University of North Carolina at Chapel Hill, Chapel Hill
ReclutandoFase 1
Edades de 18 en adelante · Todos los sexos · Actualizado el 31 jul 2026 · NCT06708897

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

  • Duke University Medical Center, Durham
ReclutandoFase 1
Edades de 18 en adelante · Todos los sexos · Actualizado el 2 jul 2026 · NCT05131022

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

  • North Carolina Basnight Cancer Hospital, Chapel Hill
Reclutando
Edades de 18 en adelante · Todos los sexos · Actualizado el 1 jul 2026 · NCT06860880

Registry of Older Patients With Cancer

  • Seby B. Jones Cancer Center, Boone
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
  • East Carolina University, Greenville
  • y 4 más
ReclutandoEstudio observacional
Edades de 65 en adelante · Todos los sexos · Actualizado el 29 jun 2026 · NCT01137825

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

  • East Carolina University, Greenville
ReclutandoFase 2
Edades de 18 en adelante · Todos los sexos · Actualizado el 19 may 2026 · NCT06588478

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

  • University of North Carolina, Chapel Hill
ReclutandoFase 1
Edades de 13 en adelante · Todos los sexos · Actualizado el 5 may 2026 · NCT04771572

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

  • Wake Forest Baptist Health, Winston-Salem
ReclutandoEstudio observacional
Edades de 18 a 120 · Todos los sexos · Actualizado el 13 abr 2026 · NCT01890486

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

  • Atrium Health /ID# 267219, Charlotte
  • Atrium Health Wake Forest Baptist Medical Center /ID# 273142, Winston-Salem
ReclutandoFase 3
Edades de 18 en adelante · Todos los sexos · Actualizado el 9 abr 2026 · NCT06428019

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

  • Duke University Medical Center, Durham
ReclutandoFase 4
Edades de 18 en adelante · Todos los sexos · Actualizado el 2 mar 2026 · NCT06876649

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

  • Duke University Medical Center, Durham
ReclutandoFase 4
Edades de 18 en adelante · Todos los sexos · Actualizado el 2 mar 2026 · NCT06876662

Study of SGR-1505 in Mature B-Cell Neoplasms

  • Duke University, Durham
ReclutandoFase 1
Edades de 18 en adelante · Todos los sexos · Actualizado el 13 feb 2026 · NCT05544019

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

  • University of North Carolina /ID# 233313, Chapel Hill
  • Novant Health Presbyterian Medical Center /ID# 230201, Charlotte
  • Novant Health Forsyth Medical Center /ID# 249533, Winston-Salem
ReclutandoFase 2
Edades de 18 en adelante · Todos los sexos · Actualizado el 9 feb 2026 · NCT04895436

Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

  • The University of North Carolina at Chapel Hill, Chapel Hill
ReclutandoFase 2
Edades de 18 en adelante · Todos los sexos · Actualizado el 7 ene 2026 · NCT06043674

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

  • Duke University, Durham
ReclutandoFase 1
Edades de 18 en adelante · Todos los sexos · Actualizado el 10 dic 2025 · NCT05602363

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
ReclutandoEstudio observacional
Edades de 18 a 120 · Todos los sexos · Actualizado el 27 oct 2025 · NCT01137643

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

  • Durham VA Medical Center, Durham, NC, Durham
ReclutandoFase 2
Edades de 18 a 80 · Todos los sexos · Actualizado el 14 oct 2025 · NCT06520098

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

  • University of North Carolina, Chapel Hill
ReclutandoFase 1
Edades de 18 en adelante · Todos los sexos · Actualizado el 2 oct 2025 · NCT05780034

CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia

  • Duke University, Durham
ReclutandoFase 1
Edades de 18 en adelante · Todos los sexos · Actualizado el 17 jul 2025 · NCT04704323

De ClinicalTrials.gov, datos obtenidos el 1 oct 2026. Cada estudio establece sus propios criterios de elegibilidad; el equipo del estudio decide quién puede participar.