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Brain Tumors clinical trials in Michigan

19 studies for Brain Tumors are looking for participants at sites in Michigan.

Cities in Michigan

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

  • Henry Ford Cancer- Detroit, Detroit
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

  • Local Institution - 0119, Ann Arbor
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

  • University of Michigan Comprehensive Cancer Center, Ann Arbor
  • Bronson Battle Creek, Battle Creek
  • University of Michigan - Brighton Center for Specialty Care, Brighton
  • and 15 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

  • C.S. MOTT Children's Hospital, University of Michigan, Ann Arbor
RecruitingPhase 2
59 Months · All sexes · Updated Sep 15, 2026 · NCT05535166

A Phase 1/1b Study of IAM1363 in HER2 Cancers

  • University of Michigan, Ann Arbor
  • Henry Ford Cancer Institute, Detroit
  • START - Midwest Cancer Research Center, Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

  • Henry Ford Hospital, Detroit
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108

Targeted Pediatric High-Grade Glioma Therapy

  • C.S. Mott Children's Hospital, Ann Arbor
RecruitingObservational study
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

  • Karmanos Cancer Institute, Detroit
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06136884

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

  • Henry Ford Health System, Detroit
RecruitingObservational study
All ages · All sexes · Updated Jul 22, 2026 · NCT04427384

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors

  • University of Michigan Comprehensive Cancer Center, Ann Arbor
RecruitingPhase 1
Ages 3 to 39 · All sexes · Updated Jun 15, 2026 · NCT06914479

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

  • University of Michigan Rogel Cancer Center, Ann Arbor
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT03550391

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

  • C.S. Mott Children's Hospital, Ann Arbor
RecruitingPhase 2
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

A Study Comparing GLIADEL to Stereotactic Radiosurgery in Metastatic Brain Disease

  • Henry Ford, Detroit
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT04222062

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

  • C.S. Mott Children's Hospital, University of Michigan, Ann Arbor
RecruitingPhase 1
Ages 4 to 25 · All sexes · Updated Mar 5, 2026 · NCT04510051

F-Tryptophan PET/CT in Human Cancers

  • Karmanos Cancer Institute, Detroit
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT05556473

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

  • Henry Ford Health System, Detroit
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT05686798

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

  • University of Michigan Health Sparrow, Lansing
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT07225101

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

  • Saint Joseph Mercy Hospital, Ann Arbor
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
  • McLaren Cancer Institute-Bay City, Bay City
  • and 16 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.