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Chronic Granulomatous Disease clinical trials recruiting in the U.S.
9 studies for Chronic Granulomatous Disease are recruiting participants at sites across the United States.
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Recently updated studies
NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)
RecruitingPhase 1
Ages 18 to 75 · Men · Updated Oct 2, 2026 · NCT05189925Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists
RecruitingPhase 1/2
Ages 4 to 65 · All sexes · Updated Oct 2, 2026 · NCT05463133Evaluation of Patients With Immune Function Abnormalities
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Sep 22, 2026 · NCT00128973Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 22, 2026 · NCT00001405Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT06605378Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease
RecruitingPhase 1/2
Ages 18 to 75 · Men · Updated Aug 13, 2026 · NCT06325709Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
RecruitingPhase 2
Ages 5 to 40 · All sexes · Updated May 15, 2026 · NCT07284641Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC
RecruitingObservational study
2 Months – 60 Years · All sexes · Updated Jan 13, 2026 · NCT04528355Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
RecruitingPhase 2
2 Months – 55 Years · All sexes · Updated Dec 15, 2025 · NCT01962415From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.