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Lung Cancer clinical trials in Washington, DC

41 studies for Lung Cancer are looking for participants at sites in and around Washington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Walter Reed National Military Medical Center, Bethesda · 7 mi away
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • George Washington University Medical Center, Washington D.C.
Ages 70 and older · All sexes · Updated Oct 5, 2026 · NCT06096844

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Kaiser Permanente-Capitol Hill Medical Center, Washington D.C.
  • MedStar Georgetown University Hospital, Washington D.C.
  • MedStar Washington Hospital Center, Washington D.C.
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • George Washington University Medical Center, Washington D.C.
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04181060

Evaluation for NCI Surgery Branch Clinical Research Protocols

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT00001823

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 3 and older · All sexes · Updated Oct 2, 2026 · NCT01441089

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 2 to 100 · All sexes · Updated Oct 2, 2026 · NCT01950572

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 2 to 120 · All sexes · Updated Oct 2, 2026 · NCT00242723

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

RecruitingPhase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT06885697

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • MedStar Georgetown University Hospital, Washington D.C.
  • MedStar Washington Hospital Center, Washington D.C.
  • Walter Reed National Military Medical Center, Bethesda · 7 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Collection of Blood From Patients With Cancer

RecruitingObservational studyHealthy volunteers welcome
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT00034216

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Maryland Oncology Hematology, P.A., Silver Spring · 7 mi away
  • Maryland Oncology Hematology, P.A., Bethesda · 7 mi away
  • Maryland Oncology Hematology, P.A., Largo · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • Georgetown University, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Washington DC Veterans Affairs Medical Center, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • MedStar Georgetown-MedStar Georgetown Transplant Institute University Hospital (MGUH), Washington D.C.
  • MEDSTAR Washington Hospital Center (MedStar Health Research Institute), Washington D.C.
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

RecruitingPhase 1/2
  • MedStar Georgetown University Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • Georgetown University Lombardi Cancer Center, Washington D.C.
  • Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Washington D.C.
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 72 · All sexes · Updated Aug 31, 2026 · NCT02133196

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • National Institutes of Health, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer

RecruitingPhase 1
  • Maryland Oncology Hematology, Calverton · 12 mi away
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07315113

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • Georgetown University Medical Center, Washington D.C.
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

Gilteritinib for the Treatment of ALK NSCLC

RecruitingPhase 1
  • Georgetown University, Washington D.C.
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06225427

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

RecruitingObservational studyHealthy volunteers welcome
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT00451022

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Kaiser Permanente-Capitol Hill Medical Center, Washington D.C.
  • Kaiser Permanente - Largo Medical Center, Largo · 11 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

RecruitingPhase 1/2
  • Georgetown University Medical Center, Washington D.C.
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06922591

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Kaiser Permanente-Capitol Hill Medical Center, Washington D.C.
  • Kaiser Permanente - Largo Medical Center, Largo · 11 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Kaiser Permanente-Capitol Hill Medical Center, Washington D.C.
  • Kaiser Permanente - Largo Medical Center, Largo · 11 mi away
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Cancer Experience Registry (CER) for Cancer Patients and Caregivers

RecruitingObservational studyHealthy volunteers welcome
  • Cancer Support Community Research & Training Institute, Washington D.C.
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT02333604

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

RecruitingPhase 3
  • The George Washington University Hospital, Washington D.C.
Ages 18 to 90 · All sexes · Updated Apr 9, 2026 · NCT06810375

Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer

RecruitingPhase 2
  • Georgetown Lombardi Comprehensive Cancer Center, Washington D.C.
  • Medstar Washington Hospital Center, Washington D.C.
Ages 18 and older · All sexes · Updated Mar 16, 2026 · NCT04499053

Erector Spinae Block for Thoracic Surgery

RecruitingPhase 4
  • The George Washington University, Washington D.C.
Ages 18 to 90 · All sexes · Updated Feb 25, 2026 · NCT05521789

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • MedStar Georgetown University Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
  • The George Washington University Cancer Center (site 212), Washington D.C.
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Silver Spring · 7 mi away
  • Massive Bio SYNERGY-AI site, Bethesda · 7 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Patient and Provider Intervention to Address Health Disparities in Lung Cancer Screening

RecruitingHealthy volunteers welcome
  • MedStar Health, Washington D.C.
Ages 50 to 80 · All sexes · Updated Dec 27, 2024 · NCT04675476

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Washington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.