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Metastatic Cancer clinical trials in Wisconsin

34 studies for Metastatic Cancer are looking for participants at sites in Wisconsin.

Cities in Wisconsin

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07562152

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

  • ThedaCare Regional Cancer Center, Appleton
  • ThedaCare Regional Medical Center - Appleton, Appleton
  • Duluth Clinic Ashland, Ashland
  • and 42 more
RecruitingPhase 2
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

  • University of Wisconsin - Carbone Cancer Center, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

  • Mayo Clinic Health System-Eau Claire Clinic, Eau Claire
  • Mayo Clinic Health System-Franciscan Healthcare, La Crosse
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05222620

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • Wisconsin Institute for Medical Research, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of ASP3082 in Adults With Advanced Solid Tumors

  • University of Wisconsin Hospital, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

  • Froedtert Hospital and the Medical College of Wisconsin, Milwaukee
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

  • The Medical College of Wisconsin, INC, Milwaukee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05875168

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • Froedtert Hospital and the Medical College of Wisconsin, Milwaukee
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

  • Minnesota Oncology Hematology, P.A., Hudson
  • Froedtert Hospital/Medical College of Wisconsin, Milwaukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

  • ThedaCare Physicians - Appleton North, Appleton
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

  • Medical College of Wisconsin, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • SSM Health Dean Medical Group - South Madison Campus Health Research/Circuit Clinical, Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06311214

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

  • Sheboygan Cancer & Blood Specialists, Sheboygan
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Biomarkers to Detect Endocrine Therapy Resistance

  • UW Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06067503

Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer

  • UW Carbone Cancer Center, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07197671

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Wisconsin, Carbone Cancer Center, Madison
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05687110

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

  • Research Site, Waukesha
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

  • University of Wisconsin, Madison
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

REMASTer: REcurrent Brain Metastases After SRS Trial

  • Medical College of Wisconsin, Milwaukee
Recruiting
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05124912

Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05674825

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

  • William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison
  • Clement J. Zablocki VA Medical Center, Milwaukee, WI, Milwaukee
RecruitingPhase 2/3
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

  • University Of Wisconsin Carbone Cancer Center - University Hospital, Madison
RecruitingPhase 2/3
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

  • UW Carbone Cancer Center, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04900818

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Milwaukee
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC)

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 15, 2025 · NCT06940440

Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

  • SSM Health Cancer Care, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2025 · NCT04295863

In Vivo Liquid Biopsy of Melanoma (Cytophone)

  • SSM Health Dean Medical Group Specialty Services, Madison
RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Mar 11, 2025 · NCT06488365

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.