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Non-Small Cell Lung Cancer clinical trials in Arkansas

34 studies for Non-Small Cell Lung Cancer are looking for participants at sites in Arkansas.

Cities in Arkansas

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07293247

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

  • Highlands Oncology Group, PA, Fayetteville
  • Highlands Oncology Group, PA, Rogers
  • Highlands Oncology Group, PA, Springdale
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

  • UAMS Winthrop P. Rockefeller Cancer Institute ( Site 0060), Little Rock
  • Highlands Oncology Group-Research Department ( Site 0062), Springdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312137

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

  • Highlands Oncology Group, Fayetteville
  • Highlands Oncology Group, Rogers
  • Highlands Oncology Group, Springdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

  • Highlands Oncology Group, PA, Fayetteville
  • Highlands Oncology Group, PA, Rogers
  • Highlands Oncology Group, PA, Springdale
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07227298

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

  • Highlands Oncology Group, Springdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06890598

Pan-tumor MRD Study

  • CARTI, Little Rock
  • Highlands Oncology Group (HOG), Springdale
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

  • Mercy Hospital Fort Smith, Fort Smith
  • CARTI Cancer Center, Little Rock
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03191149

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

  • Research Site, Little Rock
  • Research Site, Springdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06357533

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

  • Research Site, Little Rock
RecruitingPhase 2
Ages 18 to 95 · All sexes · Updated Sep 23, 2026 · NCT05061550

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

  • Clinical Study Site, Hot Springs
  • Clinical Study Sites, Jonesboro
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

  • Highlands Oncology Group - Springdale, Springdale
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Highlands Oncology Group, Springdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

  • CARTI Cancer Center ( Site 0006), Little Rock
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06422143

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

  • University of Arkansas for Medical Sciences, Little Rock
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

  • University of Arkansas, Little Rock
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

  • Highlands Oncology Group, Fayetteville
  • Highlands Oncology Group, Rogers
  • Highlands Oncology Group, Springdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

  • Mercy Hospital - FTS, Fort Smith
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07327489

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
  • University of Arkansas for Medical Sciences, Little Rock
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
  • University of Arkansas for Medical Sciences, Little Rock
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
  • University of Arkansas for Medical Sciences, Little Rock
RecruitingPhase 2
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Mercy Hospital Fort Smith, Fort Smith
  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

GEMINI-NSCLC: NSCLC Biomarker Study

  • Mercy Clinic Oncology - Fort Smith, Fort Smith
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Little Rock
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

BostonGene and Exigent Genomic INsight Study

  • Highlands Oncology Group, Rogers
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 17, 2025 · NCT06272864

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.