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Healthy volunteer studies in Springfield, MO

15 studies at sites in and around Springfield accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

RecruitingPhase 3Healthy volunteers welcome
  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO, Springfield
  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO-Screening and Recruitment Center, Springfield
Ages 18 to 49 · All sexes · Updated Sep 23, 2026 · NCT07794748

A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).

RecruitingPhase 1Healthy volunteers welcome
  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0016), Springfield
Ages 12 to 30 · All sexes · Updated Sep 17, 2026 · NCT06655324

First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

RecruitingPhase 1/2Healthy volunteers welcome
  • Research Site, Springfield
Ages 25 to 75 · All sexes · Updated Sep 14, 2026 · NCT07815678

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Springfield
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

RecruitingHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939

A Study of V132 in Healthy Older Participants (V132-001)

RecruitingPhase 1Healthy volunteers welcome
  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0002), Springfield
Ages 50 to 75 · All sexes · Updated Sep 2, 2026 · NCT07712575

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07091617

A Study of V118E in Healthy Participants (V118E-003)

RecruitingPhase 1Healthy volunteers welcome
  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0004), Springfield
Ages 18 to 49 · All sexes · Updated Jul 15, 2026 · NCT07168915

Comparison of Immediate Changes in Cervical Range of Motion Following Cervical Extension and Downslip Mobilizations.

RecruitingHealthy volunteers welcome
  • Missouri State University - Physical Therapy Clinic, Springfield
Ages 18 to 45 · All sexes · Updated Jun 18, 2026 · NCT07656285

Galleri® in the Medicare Population.

RecruitingHealthy volunteers welcome
  • Mercy Health - Springfield, Springfield
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT05673018

Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Children's Hospital - Springfield, Springfield
All ages · All sexes · Updated Apr 29, 2026 · NCT01354002

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT07215624

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.