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Esophageal Achalasia clinical trials recruiting in the U.S.

13 studies for Esophageal Achalasia are recruiting participants at sites across the United States.

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Recently updated studies

Evolution of the Chicago Classification: Bridging Physiology and Mechanics

Recruiting
Ages 18 to 85 · All sexes · Updated Sep 23, 2026 · NCT06883175

Comprehensive Esophageal Diagnostics Study

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04641702

PREcision MEDicine In Achalasia (PREMEDIA)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07293650

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07293689

Clinical Outcomes, Safety, and Effectiveness of Speedboat UltraSlim™ in Per-Oral Endoscopic Myotomy (POEM)

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT07496840

Peroral Endoscopic Myotomy for the Treatment of Achalasia

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT04640753

VZV in the Enteric Nervous System: Pathogenesis and Consequences

RecruitingPhase 4
Ages 18 to 75 · All sexes · Updated May 27, 2026 · NCT05550194

Esophageal Cancer Risk Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT00260585

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT06721520

Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders

RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT05905016

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

RecruitingObservational study
All ages · All sexes · Updated May 29, 2025 · NCT01793168

POEM-F for Achalasia International Study

Recruiting
Ages 18 to 65 · All sexes · Updated Dec 3, 2024 · NCT06042127

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.