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Cardiovascular Disease clinical trials in Tennessee

27 studies for Cardiovascular Disease are looking for participants at sites in Tennessee.

Cities in Tennessee

ELEVATE-HFpEF Clinical Study

  • Saint Thomas Research Institute, Nashville
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Improving Veteran Referral to Cardiac Rehabilitation

  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07079358

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • Alliance for Multispecialty Research, LLC-Knoxville-69693, Knoxville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

  • Stern Cardiovascular Center, Germantown
  • Ballad Health System, Greeneville
  • Apex Research Foundation, LLC, Jackson
  • and 2 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565

Product Surveillance Registry

  • Germantown
  • Memphis
  • Nashville
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Chattanooga
  • Clinical Trial Site, Chattanooga
  • Clinical Trial Site, Knoxville
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Zenith® Fenestrated+ Clinical Study

  • Holston Valley Hospital, Kingsport
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • Vanderbilt University Medical Center, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Baptist - Memphis (Stern), Memphis
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

  • The Stern Cardiovascular Foundation, Germantown
  • Apex Cardiology Research Associates of Jackson, Jackson
  • Vanderbilt Univ Medi Cen, Nashville
  • and 1 more
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

  • Vanderbilt University Medical Center, Nashville
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Meharry Medical College, Nashville
  • Nashville VA Medical Center, Nashville
  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 2
Ages 18 to 89 · All sexes · Updated Aug 27, 2026 · NCT05288790

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

  • East Tennessee Childrens Hospital, Knoxville
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

  • Research Site, Chattanooga
  • Research Site, Chattanooga
  • Research Site, Greeneville
  • and 9 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

  • Erlanger Health, Inc., Chattanooga
  • Ascension Saint Thomas, Nashville
  • Parkway Cardiology Associates, Oak Ridge
  • and 1 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Global Paradise System US Post Approval Study

  • Ascension Saint Thomas, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

  • Novartis Investigative Site, Tullahoma
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Aug 7, 2026 · NCT06813911

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Vanderbilt, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • The Stern Cardiovascular Foundation, Memphis
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 2
Ages 18 to 89 · All sexes · Updated May 26, 2026 · NCT07221214

Pivotal Study for the Cardiac Performance System (CPS)

  • The Stern Cardiovascular Foundation, Inc. / Baptist Memorial Hospital, Germantown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Centennial Medical Center, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Randomized Trial of SGLT2i in Heart Transplant Recipients

  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06625073

Gut Microbiota in Metabolic Surgery

  • Vanderbilt_University MC, Nashville
RecruitingObservational study
Ages 21 to 65 · All sexes · Updated Nov 4, 2025 · NCT05000996

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

  • Centennial Medical Center, Nashville
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs

  • Ballad CVA Heart Institute, Kingsport
Recruiting
Ages 18 and older · All sexes · Updated May 21, 2024 · NCT06424119

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.