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Endometrial Cancer clinical trials in North Carolina
31 studies for Endometrial Cancer are looking for participants at sites in North Carolina.
Cities in North Carolina
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
- Southeastern Medical Oncology Center-Clinton, Clinton
- Duke University Medical Center, Durham
- and 3 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 5, 2026 · NCT07198074Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
- Cone Health MedCenter Asheboro, Asheboro
- Cone Health Cancer Center at Alamance Regional, Burlington
- Southeastern Medical Oncology Center-Clinton, Clinton
- and 9 more
RecruitingPhase 2
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377A Study of PHST001 in Advanced Solid Tumors
- Duke Cancer Institute, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886Tirzepatide in Obesity-Driven Endometrial Cancer
- Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingEarly phase 1
Ages 18 and older · Women · Updated Oct 2, 2026 · NCT07065552A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
- Carolina Cancer Research Center, Wilson
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Duke University, Durham
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Distance-Based Exercise to Preserve Function and Prevent Disability
- Novant Health Cancer Institute - Kernersville, Kernersville
- Novant Health Cancer Institute - Mount Airy, Mount Airy
- Novant Health Forsyth Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
- Duke University Medical Center, Durham
- Duke Women's Cancer Care Raleigh, Raleigh
RecruitingPhase 2
Ages 18 and older · Women · Updated Sep 28, 2026 · NCT05112601DESTINY-PANTUMOUR04
- Research Site, Durham
- Research Site, Wilson
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
- Duke University Medical Center, Durham
- Duke Womens Cancer Care Raleigh, Raleigh
RecruitingPhase 2
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT05640999A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
- Duke Cancer Institute ( Site 6049), Durham
- FirstHealth of the Carolinas ( Site 6037), Pinehurst
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT06952504ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- UNC- Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
- Research Site, Charlotte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
- Atrium Health LCI - Morehead, Charlotte
- Atrium Health LCI - Ballantyne, Charlotte
- Atrium Health LCI - Concord, Concord
- and 3 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 9, 2026 · NCT07166094A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
- Duke Cancer Institute, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06515613DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
- Research Site, Charlotte
- Research Site, Charlotte
- Research Site, Winston-Salem
- and 1 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 3, 2026 · NCT06989112A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.
- Atrium Health - Wake Forest, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07470853FOG-001 in Locally Advanced or Metastatic Solid Tumors
- Duke University, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264A Study of DM002 in Patients With Advanced Solid Tumors
- Carolina BioOncology Institute, LLC, Huntersville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06751329Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
- Research Site, Greenville
- Research Site, Pinehurst
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
- FirstHealth of the Carolinas, Inc., Pinehurst
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 28, 2026 · NCT07022483Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
- Investigative Site #131, Raleigh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06974110The Better, Harder, Faster, Stronger Study
- Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingObservational study
Ages 55 and older · Women · Updated Jul 15, 2026 · NCT07220512Integrated Cancer Repository for Cancer Research
- Cape Fear Valley Health System, Fayetteville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
- Carolina BioOncology Institute, Huntersville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
- Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingPhase 1
Ages 18 and older · Women · Updated Jan 29, 2026 · NCT05542407A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas
- Dren Investigational Site, Huntersville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
- Levine Cancer Institute, Charlotte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2025 · NCT05997017Multimedia Aid for Genetic Testing in Gynecologic Oncology
- Univeristy of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 and older · Women · Updated Nov 12, 2025 · NCT07084168SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Chapel Hill
- Massive Bio SYNERGY-AI site, Winston-Salem
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
- FirstHealth Carolinas, Pinehurst
RecruitingPhase 2/3
Ages 18 and older · Women · Updated May 2, 2024 · NCT05797831From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.