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Esophageal Cancer clinical trials in North Carolina

16 studies for Esophageal Cancer are looking for participants at sites in North Carolina.

Cities in North Carolina

The Vanguard Study: Testing a New Way to Screen for Cancer

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Durham VA Medical Center, Durham
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • FirstHealth of the Carolinas-Moore Regional Hospital, Pinehurst
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07283939

Distance-Based Exercise to Preserve Function and Prevent Disability

  • Novant Health Cancer Institute - Kernersville, Kernersville
  • Novant Health Cancer Institute - Mount Airy, Mount Airy
  • Novant Health Forsyth Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • AdventHealth Infusion Center Asheville, Asheville
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • AdventHealth Infusion Center Haywood, Clyde
  • and 6 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma

  • Duke University Medical Center, Durham
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07603375

DESTINY-PANTUMOUR04

  • Research Site, Durham
  • Research Site, Wilson
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Pan-tumor MRD Study

  • Carolina Oncology Specialists, Charlotte
  • Southeastern Medical Oncology Center (SMOC), Goldsboro
  • Regional Medical Oncology Center, Wilson
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • Duke University Medical Center, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

  • Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07685938

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • UNC- Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

  • Research Site, Charlotte
  • Research Site, Wilmington
  • Research Site, Winston-Salem
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07431281

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

  • University of North Carolina at Chapel Hill, Chapel Hill
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT00288119

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

  • Clinical Trial Site, Huntersville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586

Integrated Cancer Repository for Cancer Research

  • Cape Fear Valley Health System, Fayetteville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chapel Hill
  • Massive Bio SYNERGY-AI site, Winston-Salem
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.