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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Florida
27 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in Florida.
Cities in Florida
Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06265285A Phase 1 Study of the Safety and Tolerability of CTX-10726
- Mayo Clinic Florida, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
- Exelixis Clinical Site #48, Celebration
- Exelixis Clinical Site #11, Gainesville
- Exelixis Clinical Site #78, Jacksonville
- and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07285044Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC
- Research Facility, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
- Moffitt Cancer Center at Speros, Land O' Lakes
- Moffitt Cancer Center at SouthShore, Ruskin
- Moffitt Cancer Center - International Plaza, Tampa
- and 4 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07227012Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
- AdventHealth Celebration, Celebration
- Lee Health Cancer Institute, Fort Myers
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
- Research Site, Jacksonville
- Research Site, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1/2
Ages 16 and older · All sexes · Updated Aug 20, 2026 · NCT05269381FOG-001 in Locally Advanced or Metastatic Solid Tumors
- Mayo Clinic, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
- University of Miami Hospital and Clinics, Miami
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma
- University of Florida, Gainesville
RecruitingPhase 2
Ages 18 to 99 · All sexes · Updated Jul 14, 2026 · NCT05669339Multi-analyte Blood Test Clinical Trial
- UF Hepatology Research at CTRB, Gainesville
- Guardian Angel Research Center, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05199259Targeted Navigation in Hepatocellular Carcinoma (HCC)
- University of Miami, Miami
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT06260943PSMA PET for the Staging and Management of Hepatocellular Carcinoma
- Miami VA Healthcare System, Miami, FL, Miami
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT07019844A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma
- Clinical Trial Site, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
- Miami VA Healthcare System, Miami, FL, Miami
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572Intravital Microscopy in Human Solid Tumors
- Mayo Clinic Florida, Jacksonville
Recruiting
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT03823144DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
- USA08-0, Florida City
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
- Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC
- Sylvester Comprehensive Cancer Center (University of Miami Hospital and Clinics), Miami
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05733598Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT06553885Phase I Clinical Study To Evaluate Pharmacokinetic Profile, Safety, Efficacy and Immunogenicity Of Ipilimumab Biosimilar HLX13 Vs. YERVOY® (US-Sourced YERVOY®) As A First-Line Treatment For Patients With Unresectable Hepatocellular Carcinoma
- Cancer Specialists of North Florida, Jacksonville
- D&H National Research Centers, LLC, Margate
- Mid Florida Hematology and oncology Center, Orange City
- and 2 more
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Mar 16, 2026 · NCT07176650Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
- Mayo Clinic in Florida, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06349642A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
- Research Site 118, Celebration
- Research Site 127, Margate
- Research Site 137, Orlando
- and 2 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Jacksonville
- Massive Bio SYNERGY-AI site, Miami
- Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 25, 2024 · NCT05824975From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.