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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Abramson Cancer Center of the University of Pennsylvania, Philadelphia
University of Pittsburgh Medical Center, Pittsburgh
WellSpan York Cancer Center, York

Ap rekriteFaz 1/2

Laj 12 ak plis · Tout sèks · Mizajou Oct 2, 2026 · NCT04585750

Distance-Based Exercise to Preserve Function and Prevent Disability

UPMC Hillman Cancer Center at Butler Health System, Butler
IRMC Cancer Center, Indiana
UPMC Hillman Cancer Center - New Castle, New Castle
ak 2 plis

Ap rekrite

Laj 18 ak plis · Tout sèks · Mizajou Oct 2, 2026 · NCT07059884

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Consultants In Med Onco And Hema, Drexel Hill
Univ of Pittsburg Med Ctr Pinnacle, Harrisburg
Allegheny Health Network, Pittsburgh

Ap rekriteFaz 3

Laj 18 a 100 · Tout sèks · Mizajou Oct 2, 2026 · NCT05827081

A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

Lehigh Valley Health Network (Data Collection Only), Allentown

Ap rekriteFaz 2

Laj 18 ak plis · Tout sèks · Mizajou Oct 2, 2026 · NCT05534438

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Lehigh Valley Hospital-Cedar Crest, Allentown
Lehigh Valley Hospital - Muhlenberg, Bethlehem
Geisinger Medical Center, Danville
ak 7 plis

Ap rekriteEtid obsèvasyonVolontè an sante akeyi

Laj 40 a 75 · Tout sèks · Mizajou Oct 2, 2026 · NCT05334069

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Alliance Cancer Specialists, Horsham
University of Pennsylvania, Abramson Cancer Center, Perelman Center for Advanced Medicine, Philadelphia
University of Pittsburgh (UPMC), Pittsburgh

Ap rekriteFaz 2

Laj 18 ak plis · Tout sèks · Mizajou Oct 1, 2026 · NCT06369285

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Penn State Milton S. Hershey Medical Center, Hershey

Ap rekriteFaz 1/2

Laj 18 ak plis · Tout sèks · Mizajou Sep 30, 2026 · NCT06324357

Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Allegheny General Hospital, Pittsburgh

Ap rekriteEtid obsèvasyon

Laj 20 a 89 · Fanm · Mizajou Sep 30, 2026 · NCT07023887

A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer

AHN Allegheny General Hospital, Pittsburgh
Allegheny General Hospital, Pittsburgh

Ap rekrite

Laj 20 a 89 · Fanm · Mizajou Sep 30, 2026 · NCT07698314

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Research Site, Pittsburgh

Ap rekriteFaz 1

Laj 18 ak plis · Tout sèks · Mizajou Sep 29, 2026 · NCT05877599

EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer

AHN Allegheny General Hospital, Pittsburgh
AHN Allegheny General Hospital, Pittsburgh

Ap rekrite

Laj 20 a 89 · Fanm · Mizajou Sep 28, 2026 · NCT07704476

Study of AVZO-021 in Patients With Advanced Solid Tumors

Avenzo Therapeutics Recruiting Site, Philadelphia

Ap rekriteFaz 1/2

Laj 18 ak plis · Tout sèks · Mizajou Sep 28, 2026 · NCT05867251

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

University of Pittsburgh Medical Center Magee-Womens Hospital ( Site 0058), Pittsburgh
Cancer Care Associates Of York ( Site 0063), York

Ap rekriteFaz 3

Laj 18 ak plis · Tout sèks · Mizajou Sep 28, 2026 · NCT07060807

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh

Ap rekrite

Laj 30 ak plis · Fanm · Mizajou Sep 25, 2026 · NCT02945579

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Thomas Jefferson University - Clinical Research Institute ( Site 0056), Philadelphia

Ap rekriteFaz 3

Laj 18 ak plis · Tout sèks · Mizajou Sep 25, 2026 · NCT06312176

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

Penn Medicine - Lancaster General Hospital, Lancaster
Capital Health Hematology Oncology Specialists, Newton
Penn Medicine - Perelman Center for Advanced Medicine, Philadelphia
ak 2 plis

Ap rekriteFaz 3

Laj 60 ak plis · Tout sèks · Mizajou Sep 25, 2026 · NCT06377852

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site, Horsham
Clinical Trial Site, Sayre

Ap rekriteFaz 3

Laj 18 ak plis · Tout sèks · Mizajou Sep 23, 2026 · NCT07085767

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Allegheny (AHN), Pittsburgh

Ap rekrite

Laj 18 ak plis · Tout sèks · Mizajou Sep 23, 2026 · NCT07214532

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

St. Luke's University Health Network, Bethlehem
Lancaster General Hospital - Ann B Barshinger Cancer Institute, Lancaster
University of Pennsylvania Hospital, Philadelphia
ak 3 plis

Ap rekriteFaz 3

Laj 18 ak plis · Tout sèks · Mizajou Sep 22, 2026 · NCT07174336

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

University of Pittsburgh Medical Center, Pittsburgh

Ap rekriteFaz 1

Laj 18 ak plis · Tout sèks · Mizajou Sep 22, 2026 · NCT07114601

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

University of Pennsylvania, Philadelphia
Fox Chase Cancer Center, Philadelphia

Ap rekriteFaz 1

Laj 18 ak plis · Tout sèks · Mizajou Sep 22, 2026 · NCT07213791

Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

University of Pennsylvania/Abramson Cancer Center, Philadelphia

Ap rekriteFaz 2

Laj 18 ak plis · Tout sèks · Mizajou Sep 18, 2026 · NCT07340541

Identifying Patterns in the Breath of Individuals With Breast Cancer

Weinstein Imaging Associates, Pittsburgh

Ap rekriteEtid obsèvasyonVolontè an sante akeyi

Laj 40 a 74 · Fanm · Mizajou Sep 18, 2026 · NCT06512350

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Lehigh Valley Health Network - Cedar Crest, Allen
Consultants In Medical Oncology and Hematology, P.C., Broomall
Penn State Milton S. Hershey Medical Center, Hershey
ak 5 plis

Ap rekriteFaz 3

Laj 18 ak plis · Tout sèks · Mizajou Sep 15, 2026 · NCT06492616

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Research Site, Pittsburgh

Ap rekriteFaz 1/2

Laj 18 ak plis · Tout sèks · Mizajou Sep 11, 2026 · NCT05123482

Active Surveillance in Older Women With ER+ Breast Cancer

University of Pittsburgh Medical Center, Pittsburgh

Ap rekriteEtid obsèvasyon

Laj 70 ak plis · Fanm · Mizajou Sep 11, 2026 · NCT07262138

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer

St. Luke's University Health Network, Bethlehem
Guthrie Medical Group, Sayre

Ap rekriteFaz 1

Laj 18 a 55 · Fanm · Mizajou Sep 9, 2026 · NCT07310420

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

Penn State Health Milton S. Hershey Medical Center, Hershey
University of Pennsylvania - Abramson Cancer Center, Philadelphia
UPMC - Hillman Cancer Center, Pittsburgh

Ap rekriteFaz 1/2

Laj 18 ak plis · Tout sèks · Mizajou Sep 8, 2026 · NCT07100106

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

University of Pennsylvania, Philadelphia

Ap rekriteFaz 1/2

Laj 18 ak plis · Tout sèks · Mizajou Sep 4, 2026 · NCT05315700

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

Penn State Cancer Institute, Hershey

Ap rekriteFaz 2

Laj 18 ak plis · Tout sèks · Mizajou Sep 3, 2026 · NCT04886531

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

UPMC Hillman Cancer Center - Magee-Women?s Hospital, Pittsburgh

Ap rekriteFaz 3

Laj 18 ak plis · Tout sèks · Mizajou Sep 3, 2026 · NCT06790693

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia

Ap rekriteFaz 1

Laj 18 ak plis · Tout sèks · Mizajou Sep 2, 2026 · NCT07216105

Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)

Abramson Cancer Center, Philadelphia

Ap rekriteEtid obsèvasyon

Laj 18 ak plis · Tout sèks · Mizajou Sep 2, 2026 · NCT05964504

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Lehigh Valley Hospital-Cedar Crest, Allentown
Lehigh Valley Hospital - Muhlenberg, Bethlehem
Bryn Mawr Hospital, Bryn Mawr
ak 56 plis

Ap rekriteFaz 3

Laj 18 a 60 · Fanm · Mizajou Sep 2, 2026 · NCT05879926

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

UPMC Hillman Cancer Center, Pittsburgh

Ap rekriteFaz 1

Laj 18 ak plis · Tout sèks · Mizajou Aug 28, 2026 · NCT07029399

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

Sidney Kimmel Comprehensive Center at Jefferson, Philadelphia
UPMC, Pittsburgh

Ap rekriteFaz 1

Laj 18 ak plis · Tout sèks · Mizajou Aug 21, 2026 · NCT06774963

Biennial CEM in Women With a Personal History of Breast Cancer

UPMC Magee-Womens Imaging - Bethel Park, Bethel Park
UPMC Magee at the Lemieux Sports Complex, Cranberry Township
Magee Womancare Monroeville, Monroeville
ak 3 plis

Ap rekriteVolontè an sante akeyi

Laj 30 a 79 · Fanm · Mizajou Aug 19, 2026 · NCT06105749

ATEMPT 2.0: Adjuvant T-DM1 vs TH

University of Pennsylvania, Abramson Cancer Center, Philadelphia
University of Pittsburgh Medical Center Cancer UPMC- Magee Women's Hospital, Pittsburgh

Ap rekriteFaz 2

Laj 18 ak plis · Tout sèks · Mizajou Aug 19, 2026 · NCT04893109

PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

Abramson Cancer Center of the University of Pennsylvania, Philadelphia

Ap rekrite

Laj 18 ak plis · Tout sèks · Mizajou Aug 19, 2026 · NCT02732171

EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer

AHN Allegheny General Hospital, Pittsburgh

Ap rekrite

Laj 20 a 89 · Fanm · Mizajou Aug 17, 2026 · NCT07739563

Sous ClinicalTrials.gov, done yo ranmase Oct 5, 2026. Chak etid gen kritè li pou li menm; ekip etid la deside ki moun ki ka patisipe.