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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

피험자 모집 중2상
  • The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles
  • Cedars-Sinai Medical Center, Los Angeles
전 연령 · 모든 성별 · 2026. 10. 5. 업데이트됨 · NCT05564377

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

피험자 모집 중1상
  • UCLA Department of Medicine-Hematology/Oncology, Los Angeles
18세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT06465069

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

피험자 모집 중1/2상
  • UCLA Jonsson Comprehensive Cancer Center, Los Angeles
  • USC Norris Comprehensive Cancer Center, Los Angeles
12세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT04585750

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

피험자 모집 중1상
  • Cedars-Sinai Medical Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT06234605

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

피험자 모집 중1상
  • University of California - Los Angeles, Los Angeles
19세 이상 · 모든 성별 · 2026. 10. 1. 업데이트됨 · NCT06586957

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

피험자 모집 중1상
  • University of California Los Angeles, Los Angeles
18세 이상 · 모든 성별 · 2026. 10. 1. 업데이트됨 · NCT06625775

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

피험자 모집 중2/3상
  • Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 29. 업데이트됨 · NCT06943755

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

피험자 모집 중1/2상
  • Children's Hospital Los Angeles, Los Angeles
  • University of California at Los Angeles, Los Angeles
25세 이하 · 모든 성별 · 2026. 9. 25. 업데이트됨 · NCT04094610

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

피험자 모집 중2/3상
  • Cedars-Sinai Cancer at Cedars-Sinai Medical Center, Los Angeles
  • UCLA Department of Medicine - Hematology/Oncology, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 25. 업데이트됨 · NCT06989437

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

피험자 모집 중3상
  • Oncura Health - Good Samaritan, Los Angeles
  • California Research Institute, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 25. 업데이트됨 · NCT07222566

Intratumoral N17350 in Advanced Solid Tumors

피험자 모집 중1/2상
  • The Angeles Clinic and Research Institute, Los Angeles
  • UCLA - Jonsson Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 23. 업데이트됨 · NCT07339176

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

피험자 모집 중1상
  • USC Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 23. 업데이트됨 · NCT06915753

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

피험자 모집 중3상
  • UCLA Hematology/Oncology - Westwood (Building 100), Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT07213804

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

피험자 모집 중3상
  • TRIO-US (Translational Research in Oncology-US), Los Angeles
  • UCLA Hematology/Oncology - Santa Monica, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT07218380

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

피험자 모집 중3상
  • USC/Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT07174336

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

피험자 모집 중1/2상
  • UCLA Hematology & Oncology ( Site 0003), Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 17. 업데이트됨 · NCT06863272

CREO - Microwave Ablation Feasibility Study

피험자 모집 중
  • Cedars Sinai, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 14. 업데이트됨 · NCT07817147

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • Clinical Study Site, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 10. 업데이트됨 · NCT07335497

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

피험자 모집 중1상
  • USC/Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 9. 업데이트됨 · NCT06440005

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

피험자 모집 중3상
  • Cedars-Sinai Medical Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 8. 업데이트됨 · NCT06119581

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

피험자 모집 중1/2상
  • Avenzo Therapeutics Recruiting Site, Los Angeles
  • Avenzo Therapeutics Recruiting Site, Los Angeles
18세 ~ 75세 · 모든 성별 · 2026. 9. 4. 업데이트됨 · NCT07038343

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • START Los Angeles, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 3. 업데이트됨 · NCT07602842

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

피험자 모집 중3상
  • Los Angeles Cancer Network, Los Angeles
  • Cedars-Sinai Cancer at Cedars-Sinai Medical Facility, Los Angeles
  • Los Angeles Cancer Network_Century City, Los Angeles
  • 외 3개
18세 이상 · 모든 성별 · 2026. 9. 2. 업데이트됨 · NCT06072612

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

피험자 모집 중1상
  • The Angeles Clinic, Los Angeles
  • UCLA, Los Angeles
18세 이상 · 모든 성별 · 2026. 9. 2. 업데이트됨 · NCT04913285

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

피험자 모집 중2상
  • University of California Los Angeles, Los Angeles
  • Samuel Oschin Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 8. 21. 업데이트됨 · NCT06769698

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

피험자 모집 중1상
  • University of California, Los Angeles (UCLA) - Division of Hematology-Oncology, Los Angeles
18세 이상 · 모든 성별 · 2026. 8. 20. 업데이트됨 · NCT05614739

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

피험자 모집 중2상
  • Research Site, Los Angeles
18세 ~ 130세 · 모든 성별 · 2026. 8. 18. 업데이트됨 · NCT06792695

FOG-001 in Locally Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • University of California, Los Angeles (UCLA), Los Angeles
18세 이상 · 모든 성별 · 2026. 8. 17. 업데이트됨 · NCT05919264

A Study of MGC026 in Participants With Advanced Solid Tumors

피험자 모집 중1상
  • The Angeles Clinic and Research Institute, Los Angeles
18세 이상 · 모든 성별 · 2026. 8. 11. 업데이트됨 · NCT06242470

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

피험자 모집 중1상
  • START Los Angeles, Los Angeles
18세 이상 · 모든 성별 · 2026. 8. 10. 업데이트됨 · NCT06880549

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

피험자 모집 중1상
  • Los Angeles General Medical Center, Los Angeles
  • USC / Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 8. 3. 업데이트됨 · NCT05687110

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

피험자 모집 중1상
  • Keck Medicine of USC Koreatown, Los Angeles
  • Los Angeles General Medical Center, Los Angeles
  • USC / Norris Comprehensive Cancer Center, Los Angeles
12세 이상 · 모든 성별 · 2026. 7. 31. 업데이트됨 · NCT05372640

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • USC Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 7. 30. 업데이트됨 · NCT04657068

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

피험자 모집 중1/2상
  • The Angeles Clinic and Research Institute, Los Angeles
12세 이상 · 모든 성별 · 2026. 7. 14. 업데이트됨 · NCT05533697

A Study of PYX-201 in Advanced Solid Tumors

피험자 모집 중1상
  • Ronald Reagan UCLA Medical Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 6. 30. 업데이트됨 · NCT05720117

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

피험자 모집 중1상
  • Cedars-Sinai Medical Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 6. 29. 업데이트됨 · NCT07458347

REMASTer: REcurrent Brain Metastases After SRS Trial

피험자 모집 중
  • UCLA, Los Angeles
18세 이상 · 모든 성별 · 2026. 6. 18. 업데이트됨 · NCT05124912

Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

피험자 모집 중2상
  • VA Greater Los Angeles Healthcare System, Los Angeles
18세 이상 · 남성 · 2026. 6. 15. 업데이트됨 · NCT05422911

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

피험자 모집 중1상
  • The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles
18세 이상 · 모든 성별 · 2026. 6. 2. 업데이트됨 · NCT06917079

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

피험자 모집 중3상
  • UCLA Hematology Oncology Santa Monica, Los Angeles
18세 이상 · 모든 성별 · 2026. 5. 18. 업데이트됨 · NCT06757634

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

피험자 모집 중2/3상
  • Helios Clinical Research, Los Angeles
18세 이상 · 모든 성별 · 2026. 5. 8. 업데이트됨 · NCT06697301

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

피험자 모집 중1/2상
  • USC Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 4. 28. 업데이트됨 · NCT06413680

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

피험자 모집 중1/2상
  • Cedars-Sinai Medical Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 4. 22. 업데이트됨 · NCT07020221

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

피험자 모집 중2/3상
  • USC Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 4. 17. 업데이트됨 · NCT06947928

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

피험자 모집 중3상
  • University of California Los Angeles, Los Angeles
18세 이상 · 모든 성별 · 2026. 4. 9. 업데이트됨 · NCT06064877

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

피험자 모집 중2/3상
  • The Angeles Clinic and Research Institute, Los Angeles
  • University of California Los Angeles, Los Angeles
전 연령 · 모든 성별 · 2026. 4. 2. 업데이트됨 · NCT06581406

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

피험자 모집 중2상
  • USC/Norris Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 3. 31. 업데이트됨 · NCT06634875

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

피험자 모집 중1상
  • USC Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 3. 20. 업데이트됨 · NCT05948865

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

피험자 모집 중1상
  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
18세 ~ 75세 · 모든 성별 · 2026. 3. 17. 업데이트됨 · NCT04119024

A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)

피험자 모집 중1/2상
  • Los Angeles General Medical Center, Los Angeles
  • USC/Norris Comprehensive Cancer Center, Los Angeles
18세 ~ 99세 · 모든 성별 · 2026. 3. 10. 업데이트됨 · NCT04333706

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

피험자 모집 중
  • Cedars-Sinai Medical Center, Los Angeles
18세 ~ 99세 · 모든 성별 · 2026. 2. 20. 업데이트됨 · NCT04907643

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

피험자 모집 중1상
  • USC - Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 2. 13. 업데이트됨 · NCT06778863

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

피험자 모집 중3상
  • Usc Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2026. 2. 6. 업데이트됨 · NCT06127407

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

피험자 모집 중1상
  • USC Norris Comprehensive Cancer Center, Los Angeles
18세 이상 · 모든 성별 · 2025. 9. 25. 업데이트됨 · NCT05808634

A Study of NX-1607 in Adults With Advanced Malignancies

피험자 모집 중1상
  • University of Southern California, Los Angeles
18세 이상 · 모든 성별 · 2025. 9. 9. 업데이트됨 · NCT05107674

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

피험자 모집 중1/2상
  • University of Southern California, Los Angeles
18세 이상 · 모든 성별 · 2025. 8. 17. 업데이트됨 · NCT05394103

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