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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

피험자 모집 중2상
  • UPMC-Magee Womens Hospital, Pittsburgh
  • UPMC Hillman Cancer Center, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
  • 외 3개
전 연령 · 모든 성별 · 2026. 10. 5. 업데이트됨 · NCT05564377

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

피험자 모집 중1상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT05372614

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

피험자 모집 중1/2상
  • University of Pittsburgh Medical Center, Pittsburgh
12세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT04585750

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

피험자 모집 중2/3상
  • University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 29. 업데이트됨 · NCT06943755

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

피험자 모집 중1상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 29. 업데이트됨 · NCT05803382

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

피험자 모집 중1상
  • University of Pittsburgh Medical Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT07114601

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

피험자 모집 중3상
  • AHN Allegheny General Hospital, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT07218380

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

피험자 모집 중1/2상
  • Allegheny Health Network, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT06128551

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

피험자 모집 중1/2상
  • UPMC Hillman Cancer Center ( Site 0014), Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 17. 업데이트됨 · NCT06863272

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • Clinical Study Site, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 10. 업데이트됨 · NCT07335497

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

피험자 모집 중3상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 8. 업데이트됨 · NCT06119581

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

피험자 모집 중1상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 9. 8. 업데이트됨 · NCT04585958

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

피험자 모집 중1상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 8. 28. 업데이트됨 · NCT07029399

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

피험자 모집 중1상
  • Allegheny General Hospital, Pittsburgh
  • University of Pittsburgh Medical Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 8. 20. 업데이트됨 · NCT05614739

FOG-001 in Locally Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 8. 17. 업데이트됨 · NCT05919264

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

피험자 모집 중1/2상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 7. 31. 업데이트됨 · NCT05691491

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

피험자 모집 중3상
  • Research Site, Pittsburgh
  • Research Site, Pittsburgh
18세 이상 · 여성 · 2026. 7. 29. 업데이트됨 · NCT07044336

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

피험자 모집 중1상
  • University of Pittsburg Medical Center _UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 7. 15. 업데이트됨 · NCT06657144

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

피험자 모집 중3상
  • AHN Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 6. 25. 업데이트됨 · NCT06216301

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

피험자 모집 중1상
  • University of Pittsburg Medical Center (UPCM), Pittsburgh
18세 이상 · 모든 성별 · 2026. 6. 11. 업데이트됨 · NCT05283330

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

피험자 모집 중2/3상
  • University of Pittsburgh Medical Center(UPMC)-Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 5. 8. 업데이트됨 · NCT06697301

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

피험자 모집 중1/2상
  • University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 4. 28. 업데이트됨 · NCT06413680

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

피험자 모집 중2/3상
  • UPMC Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 4. 17. 업데이트됨 · NCT06947928

Window of Opportunity in Preserving Laryngeal Function Trial

피험자 모집 중2상
  • UPMC Hillman Cancer, Pittsburgh
18세 이상 · 모든 성별 · 2026. 4. 13. 업데이트됨 · NCT07423078

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

피험자 모집 중3상
  • University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 4. 9. 업데이트됨 · NCT06064877

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

피험자 모집 중2/3상
  • UPMC Hillman Cancer Center, Pittsburgh
전 연령 · 모든 성별 · 2026. 4. 2. 업데이트됨 · NCT06581406

Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

피험자 모집 중1상
  • Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 3. 6. 업데이트됨 · NCT06171750

Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)

피험자 모집 중2상
  • Allegheny Health Network West Penn Hospital, Pittsburgh
18세 ~ 80세 · 모든 성별 · 2026. 2. 27. 업데이트됨 · NCT07282834

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

피험자 모집 중3상
  • University of Pittsburgh Medical Center-Hillman Cancer Center, Pittsburgh
18세 이상 · 모든 성별 · 2026. 2. 6. 업데이트됨 · NCT06127407

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

피험자 모집 중1/2상
  • University of Pittsburgh, Pittsburgh
18세 이상 · 모든 성별 · 2024. 12. 20. 업데이트됨 · NCT05877430

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