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Metastatic Cancer clinical trials in Detroit, MI

24 studies for Metastatic Cancer are looking for participants at sites in and around Detroit (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

RecruitingPhase 2/3
  • Henry Ford Cancer- Detroit, Detroit
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

RecruitingPhase 1/2
  • Henry Ford Cancer Institute, Detroit
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

RecruitingPhase 1
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Clinical Study Site, Detroit
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07335497

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Henry Ford Cancer Institute/Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

RecruitingPhase 1/2
  • Crinetics Study Site, Detroit
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07129252

A Study of ASP1002 in Adults for Treatment of Solid Tumors

RecruitingPhase 1
  • Henry Ford Hospital, Detroit
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05719558

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #120, Detroit
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06974110

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Henry Ford Hospital, Detroit
Ages 12 and older · All sexes · Updated Jul 14, 2026 · NCT05533697

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Recruiting
  • Henry Ford Hospital, Detroit
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05023772

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

RecruitingPhase 1/2
  • Henry Ford Cancer Institute, Detroit
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT05384626

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT05735080

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

RecruitingPhase 1
  • Henry Ford Cancer Center, Detroit
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT06521554

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

RecruitingPhase 1
  • Henry Ford Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT05856981

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

RecruitingPhase 1
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT05808634

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

Metastatic Cancer trials in other cities

Other studies in Detroit

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.