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Treatment-Resistant Depressive Disorder clinical trials in Massachusetts
7 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Massachusetts.
Cities in Massachusetts
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
- Adams Clinical, Inc., Watertown
- Vitalix Clinical, Inc., Worcester
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07284667One-Day cTBS Over the Precuneus
- McLean Hospital, Belmont
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07758010Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
- Massachusetts General Hospital's Depression and Clinical Research program, Boston
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07563868A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- Elixia MA, Springfield
- Adams Clinical, Watertown
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830ALTO-207 in Adults With Treatment-resistant Depression (TRD)
- Site 7166, Worcester
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 28, 2026 · NCT07553637From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.