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Breast Cancer clinical trials in South Carolina
23 studies for Breast Cancer are looking for participants at sites in South Carolina.
Cities in South Carolina
- Greenville12 studies
- Charleston12 studies
- Spartanburg6 studies
- Greer4 studies
- Florence4 studies
- Easley3 studies
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
- Bon Secours St Francis Cancer Center, Greenville
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- AnMed Health Cancer Center, Anderson
- Prisma Health Richland Hospital, Columbia
- McLeod Regional Medical Center, Florence
- and 12 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069CBD for Breast Cancer Primary Tumors
- Medical University of South Carolina, Charleston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06148038The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
- St. Joseph's Candler Bluffton Campus, Bluffton
- SC Cancer Specialists - Hilton Head at St. Joseph's/Candler, Hilton Head Island
- Levine Cancer Institute, Rock Hill
RecruitingPhase 3
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT06377852A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
- Medical University of South Carolina-Hollings Cancer Center ( Site 0016), Charleston
- St Francis Cancer Center ( Site 0093), Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
- Medical University of South Carolina, Charleston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
- Hollings Cancer Center, Charleston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
- Spartanburg Regional Healthcare System, Spartanburg
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05315700A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
- Bon Secours - St. Francis Hospital, Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06790693Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Prisma Health Cancer Institute - Spartanburg, Boiling Springs
- Medical University of South Carolina, Charleston
- and 14 more
RecruitingPhase 3
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
- St Francis Cancer Center, Greenville
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06926868E-Mindfulness Approaches for Living After Breast Cancer
- Beaufort Memorial Hospital, Beaufort
- Prisma Health Cancer Institute - Spartanburg, Boiling Springs
- Medical University of South Carolina, Charleston
- and 10 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
- Medical University of South Carolina, Charleston
RecruitingPhase 2
Ages 18 to 55 · Women · Updated Jul 27, 2026 · NCT06184750Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
- Prisma Health - Upstate (ITOR)_Edenfield ( Site 0053), Greenville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06686394Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
- Medical University of South Carolina, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT04468061De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Medical University of South Carolina, Charleston
- McLeod Regional Medical Center, Florence
- and 5 more
RecruitingPhase 3
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
- AnMed Health Cancer Center, Anderson
- Beaufort Memorial Hospital, Beaufort
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- and 18 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- Medical University of South Carolina, Charleston
- McLeod Health, Florence
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
- Spartanburg Medical Center, Spartanburg
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Greenville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
- Prisma Health Cancer Institute - Butternut, Greenville
- Prisma Health Cancer Institute - Faris, Greenville
- Prisma Health Cancer Institute - Eastside, Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
- Roper St. Francis Physician Partners - Breast Surgery, Charleston
- Tidelands Health Coastal Carolina Breast Center, Georgetown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients
- Prisma Health Cancer Institute, Greenville
RecruitingObservational study
Ages 20 and older · Women · Updated Nov 4, 2024 · NCT06672497From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.