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Crohn's Disease clinical trials in California

37 studies for Crohn's Disease are looking for participants at sites in California.

Cities in California

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

  • Clinnova Research /ID# 280509, Anaheim
  • Southern California Res. Ctr /ID# 280476, Coronado
  • Gastro Care Institute /ID# 281071, Lancaster
  • and 2 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 5, 2026 · NCT07697456

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

  • University of California Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT03816345

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

  • Clinnova Research ( Site 5110), Anaheim
  • Southern California Research Center ( Site 5044), Coronado
  • Om Research LLC ( Site 5038), Lancaster
  • and 5 more
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

  • Gastroenterology and Liver Institute, Escondido
  • United Clinical Research Institute, Murrieta
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT06581328

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

  • Southern California Res. Ctr /ID# 265549, Coronado
  • UC San Diego Health System /ID# 265565, La Jolla
  • uc davis medical center - patient support services building /ID# 265554, Sacramento
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

  • Cedars Sinai Medical Center, Los Angeles
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Sep 25, 2026 · NCT05923073

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

  • United Medical Doctors, Murrieta
  • UCI Health, Orange
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06233461

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

  • Clinnova Research, Anaheim
  • Gastro Care Institute, Lancaster
  • United Gastroenterologists, Los Alamitos
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07499232

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

  • Clinnova Research, Anaheim
  • Southern California Research Center, Coronado
  • Om Research, LLC 1, Lancaster
  • and 6 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07196722

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Smart Cures Clinical Research, Anaheim
  • Cedars-Sinai Medical Center, Beverly Hills
  • United Medical Doctors - Los Alamitos, Los Alamitos
  • and 1 more
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

  • Alliance Research Institute-Site Number: 8400008, Canoga Park
  • Southern California GI & Liver Centers-Site Number: 8400062, Coronado
  • Gastroenterology and Liver Institute - Escondido-Site Number: 8400146, Escondido
  • and 14 more
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

  • UCSF Benioff Children's Hospital - Oakland /ID# 258327, Oakland
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Sep 23, 2026 · NCT05995353

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

  • UCSF Medical Center at Mission Bay, San Francisco
RecruitingPhase 3
Ages 2 to 19 · All sexes · Updated Sep 22, 2026 · NCT04844606

A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

  • Biopharma Informatic, LLC, Los Angeles
  • Om Research LLC, Oxnard
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07483099

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

  • Gastro Care Institute, Lancaster
  • Infinity Clinical Research, San Diego
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 22, 2026 · NCT06226883

A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

  • Biopharma Informatic, LLC, Los Angeles
  • Om Research LLC, Oxnard
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07483073

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

  • University of California San Diego Health (UCSD), La Jolla
  • Cedars-Sinai Medical Center, Los Angeles
  • Hoag Hospital Newport Beach, Newport Beach
RecruitingPhase 4
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

  • Clinnova Research, Anaheim
  • Gastro SB Clinic, Chula Vista
  • United Medical Doctors, Los Alamitos
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07577843

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

  • Cedars Sinai Medical Center, Los Angeles
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Aug 24, 2026 · NCT05509777

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

  • Hoag Hospital, Irvine
  • UC San Diego Health, La Jolla
  • Cedars-Sinai, Los Angeles
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT05230173

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

  • Children's Hospital Of Orange County, Orange
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Aug 3, 2026 · NCT06100289

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

  • UCSF Benioff Children's Hospital - Oakland /ID# 262217, Oakland
  • Lucile Packard Children's Hospital /ID# 262193, Palo Alto
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Jun 24, 2026 · NCT06332534

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

  • Loma Linda University, Loma Linda
  • Children's Hospital of Orange County, Orange
  • Stanford Children's Health, Palo Alto
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Jun 22, 2026 · NCT06405087

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

  • Cedars-Sinai Medical Center, Beverly Hills
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Jun 5, 2026 · NCT06976853

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

  • UCSD Medical Center, La Jolla
  • Keck Medicine Of USC - USC Healthcare Center 1, Los Angeles
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated May 27, 2026 · NCT06227910

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

  • Cedars-Sinai, Los Angeles
  • UCSF Benioff Children's Hospitals, San Francisco
RecruitingPhase 4
Ages 6 to 17 · All sexes · Updated May 27, 2026 · NCT05781152

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

  • Rady Children's Hospital - San Diego - PIN, San Diego
RecruitingPhase 3
Ages 2 and older · All sexes · Updated May 7, 2026 · NCT05442567

Precise Infliximab Exposure and Pharmacodynamic Control

  • Children's Hospital of Los Angeles, Los Angeles
  • Lucile Packard Children's Hospital Stanford, Palo Alto
  • Rady Children's Hospital San Diego, San Diego
RecruitingPhase 2/3
Ages 6 to 22 · All sexes · Updated May 5, 2026 · NCT05660746

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

  • Rady Childrens Hospital San Diego - PIN, San Diego
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated May 5, 2026 · NCT04779320

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

  • Hoag Hospital, Irvine
  • United Medical Doctors, Murrieta
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

  • Investigational Site Number: 8400005, Escondido
  • Investigational Site Number: 8400001, Lancaster
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Mar 27, 2026 · NCT06958536

Effect of Statins on Crohn's Disease

  • Stanford University, Stanford
RecruitingEarly phase 1
Ages 18 to 80 · All sexes · Updated Feb 27, 2026 · NCT06538649

Impact of Prebiotics in Ulcerative Colitis

  • UCLA, Los Angeles
Recruiting
Ages 18 to 85 · All sexes · Updated Feb 27, 2026 · NCT06495658

Stem Cell Transplantation in Crohn's Disease

  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 1/2
Ages 13 to 28 · All sexes · Updated Feb 20, 2026 · NCT04224558

Treatment of Moderate to Severe Refractory Crohn's Disease

  • University of California, Davis, Sacramento
  • University of California, San Francisco, San Francisco
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Dec 10, 2025 · NCT06721962

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

  • University of California, San Diego, La Jolla
RecruitingObservational study
All ages · Women · Updated Jan 28, 2025 · NCT02103361

Urine Metabolites in the Diagnosis of Disease

  • Unio Health Partners (Gastroenterology), Encinitas
  • Digestive Health Associates, Santa Monica
  • Westside Gastro Care, Santa Monica
  • and 1 more
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Dec 13, 2024 · NCT06710067

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.