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Crohn's Disease clinical trials recruiting in the U.S.
89 studies for Crohn's Disease are recruiting participants at sites across the United States.
Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.
Cities with the most studies
- New York City, NY33 studies
- St. Louis, MO19 studies
- Miami, FL19 studies
- Orlando, FL19 studies
- Boston, MA18 studies
- Houston, TX17 studies
- Atlanta, GA16 studies
- Tyler, TX16 studies
- San Diego, CA15 studies
- Cleveland, OH15 studies
- Colorado Springs, CO14 studies
- San Antonio, TX14 studies
- Los Angeles, CA13 studies
- Philadelphia, PA11 studies
- Tampa, FL11 studies
- Washington, DC10 studies
- Cincinnati, OH10 studies
- Durham, NC10 studies
- Providence, RI10 studies
- Tacoma, WA10 studies
- Baltimore, MD10 studies
- Seattle, WA10 studies
- Indianapolis, IN9 studies
- Lubbock, TX9 studies
- Evanston, IL9 studies
- Pittsburgh, PA9 studies
- Louisville, KY8 studies
- Lewisville, TX8 studies
- Rochester, MN8 studies
- Dallas, TX8 studies
- Milwaukee, WI8 studies
- Chicago, IL8 studies
- Independence, MO8 studies
- Scottsdale, AZ7 studies
- Lancaster, CA7 studies
- Charlotte, NC7 studies
- Lafayette, LA7 studies
- New Haven, CT7 studies
- Peoria, AZ7 studies
- Ann Arbor, MI7 studies
By state
- Alabama9 studies
- Arizona16 studies
- Arkansas4 studies
- California35 studies
- Colorado18 studies
- Connecticut12 studies
- District of Columbia4 studies
- Florida26 studies
- Georgia20 studies
- Idaho4 studies
- Illinois17 studies
- Indiana13 studies
- Iowa8 studies
- Kansas11 studies
- Kentucky11 studies
- Louisiana11 studies
- Maryland15 studies
- Massachusetts25 studies
- Michigan17 studies
- Minnesota10 studies
- Mississippi3 studies
- Missouri22 studies
- Nevada8 studies
- New Hampshire3 studies
- New Jersey8 studies
- New York35 studies
- North Carolina17 studies
- Ohio28 studies
- Oklahoma7 studies
- Oregon4 studies
- Pennsylvania21 studies
- Rhode Island10 studies
- South Carolina14 studies
- South Dakota3 studies
- Tennessee11 studies
- Texas34 studies
- Utah7 studies
- Virginia15 studies
- Washington20 studies
- Wisconsin8 studies
Recently updated studies
Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 13 to 20 · All sexes · Updated Nov 13, 2026 · NCT04508088Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04751396Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345A Study of SL-325 in Crohn's Disease Patients
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT07753850Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
RecruitingPhase 3
All ages · All sexes · Updated Nov 10, 2026 · NCT06651281Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease
RecruitingObservational study
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07619547A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Nov 10, 2026 · NCT06430801Iron Treatment for Iron Deficiency Anemia in Children and Young Adults With Crohn's Disease
RecruitingPhase 4
Ages 3 to 21 · All sexes · Updated Nov 9, 2026 · NCT07925450A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT07483073Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Nov 4, 2026 · NCT06937099A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06226883A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT07483099A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07196722A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07577843A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
RecruitingPhase 3
Ages 3 and older · All sexes · Updated Nov 3, 2026 · NCT06663332A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
RecruitingPhase 4
Ages 18 and older · Women · Updated Nov 3, 2026 · NCT07654751A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Nov 3, 2026 · NCT05923073A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07499232A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT04372108An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Nov 2, 2026 · NCT03167437A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Nov 2, 2026 · NCT06233461A Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's Disease
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Nov 2, 2026 · NCT06958536A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Oct 28, 2026 · NCT06581328Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 27, 2026 · NCT07697456Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06997965From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.