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Crohn's Disease clinical trials in Tyler, TX

16 studies for Crohn's Disease are looking for participants at sites in and around Tyler (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

RecruitingPhase 3
  • Tyler Research Institute ( Site 0294), Tyler
All ages · All sexes · Updated Oct 2, 2026 · NCT06651281

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

RecruitingPhase 3
  • Tyler Research Institute ( Site 5001), Tyler
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

RecruitingPhase 2
  • Tyler Research Institute /ID# 265545, Tyler
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • The University of Texas Health Science Center at Tyler, Tyler
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07499232

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2/3
  • Tyler Research Institute, LLC, Tyler
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07196722

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • Tyler Research Institute, LLC, Tyler
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06233461

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Tyler Research Institute, Tyler
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Tyler Research Institute, LLC-Site Number: 8400095, Tyler
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Tyler Research Institute LLC-Site Number: 8400095, Tyler
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184944

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • Tyler Research Institute, LLC, Tyler
Ages 18 to 85 · All sexes · Updated Sep 22, 2026 · NCT06226883

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

RecruitingPhase 4
  • Tyler Research Institute, LLC, Tyler
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Tyler Research Institute, LLC, Tyler
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07577843

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

RecruitingPhase 3
  • Tyler Research Institute, LLC, Tyler
Ages 18 to 65 · All sexes · Updated May 27, 2026 · NCT06227910

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

RecruitingPhase 2
  • Tyler Research Institute, LLC, Tyler
Ages 18 to 75 · All sexes · Updated May 22, 2026 · NCT06764615

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • Tyler Research Institute, LLC, Tyler
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

RecruitingPhase 2
  • Mirador Therapeutics Selected Site, Tyler
Ages 18 to 80 · All sexes · Updated Mar 12, 2026 · NCT07113522

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in Tyler

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.