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Esophageal Cancer clinical trials in California
41 studies for Esophageal Cancer are looking for participants at sites in California.
Cities in California
- Los Angeles15 studies
- Baldwin Park14 studies
- San Diego10 studies
- Santa Monica7 studies
- Mountain View7 studies
- Orange6 studies
- Irvine5 studies
- Concord4 studies
- San Francisco4 studies
- Sacramento4 studies
- Fullerton3 studies
- Stockton3 studies
- Santa Rosa3 studies
The Vanguard Study: Testing a New Way to Screen for Cancer
- Kaiser Permanente-Division of Research, Pleasanton
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
- City of Hope National Medical Center, Duarte
- University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla
- UCLA Department of Medicine-Hematology/Oncology, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)
- UCLA Hematology/Oncology - Santa Monica ( Site 4905), Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05319730A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- City of Hope - Duarte Cancer Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
- Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
- Mercy Cancer Center - Carmichael, Carmichael
- Mercy San Juan Medical Center, Carmichael
- and 8 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07283939Distance-Based Exercise to Preserve Function and Prevent Disability
- Kaiser Permanente Dublin, Dublin
- Kaiser Permanente-Fremont, Fremont
- Kaiser Permanente Fresno Orchard Plaza, Fresno
- and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
- PCR Oncology, Arroyo Grande
- AIS Cancer Center at San Joaquin Community Hospital, Bakersfield
- and 20 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- City of Hope, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
- City of Hope National Medical Center, Duarte
- City of Hope at Irvine Lennar, Irvine
- Ronald Reagan UCLA Medical Center, Los Angeles
- and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499DESTINY-PANTUMOUR04
- Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
- Precision NextGen Oncology, Beverly Hills
- OPN Healthcare, Inc, Glendale
- University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379Pan-tumor MRD Study
- Los Angeles Cancer Network (LACN), Glendale
- Ventura County Hematology Oncology Specialists, Oxnard
- Medical Oncology Associates of San Diego (MOASD), San Diego
- and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404A Study of LY4257496 in Participants With Cancer (OMNIRAY)
- City of Hope, Duarte
- University of California, Los Angeles (UCLA), Santa Monica
- Stanford University Medical Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
- Hoag Memorial Hospital Presbyterian, Newport Beach
- Stanford University Medical Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- UC IRVINE Health, Orange
- UC Davis Comprehensive Cancer Center, Sacramento
- Stanford Cancer Institute, Stanford
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
- Beverly Hills Cancer Center, Beverly Hills
- City of Hope Cancer Center, Duarte
- University of California Irvine Medical Center, Orange
- and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.
- Helios CR Inc./RadNet, Cerritos
- City of Hope National Cancer Center, Duarte
- Hoag Memorial Hospital, Irvine
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07217704ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- University of California, San Diego, La Jolla
- Hoag Memorial Hospital Presbyterian, Newport Beach
- Redwood City, Redwood City
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
- City of Hope, Duarte
- START - Los Angeles, Los Angeles
- Cedars Sinai, Los Angeles
- and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
- Research Site, Duarte
- Research Site, Fountain Valley
- Research Site, Fullerton
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07431281Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
- UCLA Hematology/Oncology - Santa Monica ( Site 8905), Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06445972Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
- UCLA Hematology/Oncology - Santa Monica ( Site 6905), Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06469944Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)
- Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT07795749Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA
- UCLA, Santa Monica
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07070466A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
- UC San Diego Moores Cancer Center, San Diego
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers
- University of California, San Francisco, San Francisco
- John Muir Medical Center-Walnut Creek, Walnut Creek
Recruiting
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT04221893A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
- UCSD, La Jolla
- Sharp Healthcare, San Diego
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835A Study of Sigvotatug Vedotin in Advanced Solid Tumors
- Providence Medical Foundation, Anaheim
- Providence Medical Foundation, Fullerton
- Providence St. Jude Medical Center Virginia K Crosson and Infusion Center, Fullerton
- and 7 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
- City of Hope National Medical Center /ID# 276272, Duarte
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 278589, Irvine
- USC Norris Comprehensive Cancer Center /ID# 279603, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT05005403Proton Therapy for Esophageal Cancer
- Loma Linda University Medical Center, Loma Linda
Recruiting
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT01684904Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
- Beckman Research Institute of City of Hope, Duarte
- VA Medical Center, Fresno, Fresno
- Santa Clara Valley Medical Center, Fruitdale
- and 5 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
- Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 99 · All sexes · Updated Feb 20, 2026 · NCT04907643cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- City of Hope, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- Stanford University School of Medicine, Stanford
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT01048281A Study of MT-4561 in Patients With Various Advanced Solid Tumors
- University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06943521VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
- Providence Medical Foundation (site 209), Santa Rosa
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Duarte
- Massive Bio SYNERGY-AI site, Irvine
- Massive Bio SYNERGY-AI site, La Jolla
- and 3 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)
- Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 15, 2025 · NCT0712435164Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
- City of Hope, Duarte
- UC Irvine Health - Chao Family Comprehensive Cancer Center, Orange
- Stanford Hospital & Clinics, Stanford
RecruitingPhase 1/2
Ages 15 and older · All sexes · Updated Aug 12, 2025 · NCT06298916A Beta-only IL-2 ImmunoTherapY Study
- Sharp Memorial Hospital, San Diego
- Providence Saint John's Health Center, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.