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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Massachusetts
19 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in Massachusetts.
Cities in Massachusetts
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
- Exelixis Clinical Site #7, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483National Liver Cancer Screening Trial
- Massachusetts General Hospital, Boston
RecruitingPhase 4
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
- Mass General Cancer Center, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Sep 23, 2026 · NCT07219459Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
- Mass General Brigham, Boston
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119FOG-001 in Locally Advanced or Metastatic Solid Tumors
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
- Massachusetts General Hospital Cancer Center, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours
- Research Site, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06795022A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
- Tufts Medical Center, Boston
- Massachusetts General Hospital, Boston
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston
RecruitingPhase 1/2
Ages 1 to 21 · All sexes · Updated Jul 6, 2026 · NCT04634357Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
- Mass General Brigham Cancer Institute, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 16 and older · All sexes · Updated Jun 2, 2026 · NCT07197554Computer Guided Microwave Liver Ablation
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 90 · All sexes · Updated May 11, 2026 · NCT07226869Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma
- Children's Hospital Boston, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 2
Ages 0 to 30 · All sexes · Updated Feb 24, 2026 · NCT04134559Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
- Massachussets General Hospital, Boston
RecruitingPhase 4
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Worcester
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis
- Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 26, 2025 · NCT06265272Psychoeducational Intervention for Patients With Hepatocellular Carcinoma
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Aug 29, 2025 · NCT06541990From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.