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Prostate Cancer clinical trials in Florida

100 studies for Prostate Cancer are looking for participants at sites in Florida.

Cities in Florida

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
  • Advent Health, Orlando
  • Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06625034

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Malcom Randall Veterans Administration Medical Center, Gainesville
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
  • Morton Plant Hospital, Clearwater
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Jupiter Medical Center, Jupiter
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Holy Cross Hospital, Fort Lauderdale
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men

  • Mayo Clinic in Florida, Jacksonville
RecruitingHealthy volunteers welcome
Ages 21 to 80 · All sexes · Updated Sep 29, 2026 · NCT06541210

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

  • Baptist Health South Florida Inc, Boca Raton
Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256

DESTINY-PANTUMOUR04

  • Research Site, Coral Springs
  • Research Site, St. Petersburg
  • Research Site, West Palm Beach
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

  • Moffitt Cancer Center, Tampa, Tampa
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07319871

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • Mount Sinai Braman Comprehensive Cancer Center ( Site 0107), Miami Beach
  • Memorial Hospital West-Memorial Cancer Institute ( Site 0109), Pembroke Pines
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men

  • Mayo Clinic in Florida, Jacksonville
Recruiting
All ages · Men · Updated Sep 25, 2026 · NCT07126548

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07082920

A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer

  • Florida Cancer Specialists & Research Institute, Sarasota
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07746713

Precise Oncology Interventions in Nutrition and Training (OnPoint)

  • University of Miami, Miami
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06534918

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • Moffitt Cancer Center, Tampa
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  • Florida Cancer Specialists, Fort Myers
  • Baptist Health South, Miami
  • AdventHealth, Orlando
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Hialeah
  • Research Site, Jacksonville
  • Research Site, Tampa
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

  • North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville
  • Orlando VA Medical Center, Orlando, FL, Orlando
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

  • Orlando VA Medical Center, Orlando, FL, Orlando
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077), Jacksonville
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Biogenix Molecular, LLC, Miami
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07581184

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • University of Miami, Miami
  • AdventHealth, Orlando
  • Advanced Urology Institute, Oxford
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

  • Mayo Clinic- Jacksonville, Jacksonville
  • Biogenix Molecular, LLC, Miami
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy

  • Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 45 and older · Men · Updated Sep 11, 2026 · NCT06940271

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Bay Pines VA Healthcare System, Bay Pines
  • Jupiter Medical Center, Jupiter
  • and 6 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • Florida Cancer Specialist, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer

  • Research Site, Orlando
RecruitingPhase 1/2
Ages 18 to 100 · Men · Updated Sep 9, 2026 · NCT07529717

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

  • Sarah Cannon Research Institute @ Florida Cancer, Orlando
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 8, 2026 · NCT05800665

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

  • H. Lee Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer

  • Research Site, Orlando
  • Research Site, Tampa
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT07192614

UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning

  • Univeristy of Florida Health Proton Therapy Institute, Jacksonville
Recruiting
Ages 18 to 100 · Men · Updated Aug 27, 2026 · NCT06465966

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

  • Research Site, Miami
  • Research Site, Tampa
RecruitingPhase 1/2
Ages 18 to 99 · Men · Updated Aug 27, 2026 · NCT07590934

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.