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Клинички испитувања за Акутна миелоидна леукемија во Северна Каролина

43 студии за Акутна миелоидна леукемија бараат учесници на локации во Северна Каролина.

Градови во Северна Каролина

Официјален текст на студијата (англиски)

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
  • и уште 5
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 5.10.2026 · NCT05564390

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • AdventHealth Infusion Center Asheville, Asheville
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • AdventHealth Infusion Center Haywood, Clyde
  • и уште 6
Се регрутираНабљудувачка студијаДобредојдени се здрави волонтери
Возраст од 40 до 75 · Сите полови · Ажурирано 2.10.2026 · NCT05334069

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

  • Wake Forest University Health Sciences, Winston-Salem
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 1.10.2026 · NCT06484062

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
  • Duke University Medical Center, Durham
  • и уште 3
Се регрутираФаза 2
Возраст од 18 до 59 · Сите полови · Ажурирано 28.9.2026 · NCT05554393

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

  • Atrium Health, Charlotte
  • Novant Health Charlotte, Charlotte
  • Carolina Oncology Specialists, Charlotte
  • и уште 2
Се регрутираФаза 3
Возраст 18 и постари · Сите полови · Ажурирано 25.9.2026 · NCT06852222

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Duke University Medical Center, Durham
  • East Carolina University, Greenville
  • и уште 1
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 22.9.2026 · NCT06672146

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Duke University Medical Center, Durham
  • East Carolina University, Greenville
  • и уште 1
Се регрутираФаза 2
Возраст од 18 до 59 · Сите полови · Ажурирано 22.9.2026 · NCT05554406

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Duke University Medical Center, Durham
  • East Carolina University, Greenville
  • и уште 1
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 22.9.2026 · NCT06317649

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

  • Mission Hospital, Asheville
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • и уште 4
Се регрутираФаза 3
6 Months – 21 Years · Сите полови · Ажурирано 17.9.2026 · NCT04293562

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

  • Duke University Medical Center, Durham
Се регрутираФаза 1/2
30 Days · Сите полови · Ажурирано 16.9.2026 · NCT04065399

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

  • Novant Health Clinical Research, Charlotte
  • East Carolina University, Greenville
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 16.9.2026 · NCT06824168

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

  • University of North Carolina at Chapel Hill, Chapel Hill
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 14.9.2026 · NCT06846606

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

  • UNC School of Medicine, Division of Hematology, Chapel Hill
Се регрутираФаза 1/2
Возраст 12 и постари · Сите полови · Ажурирано 3.9.2026 · NCT04588922

Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax

  • Atrium Health Wake Forest Baptist Medical Center, Winston-Salem
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 2.9.2026 · NCT07471841

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

  • US-Chapel Hill-UNCNORTHCAROLINA, Chapel Hill
Се регрутираФаза 3
Возраст 18 и постари · Сите полови · Ажурирано 2.9.2026 · NCT06652438

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

  • Novant Health Weisiger Cancer Institute, Charlotte
Се регрутираНабљудувачка студија
Возраст 0 и постари · Сите полови · Ажурирано 2.9.2026 · NCT07154823

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

  • Mission Hospital, Asheville
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • и уште 4
Се регрутираФаза 1/2
До возраст 22 · Сите полови · Ажурирано 25.8.2026 · NCT04726241

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Wake Forest University Health Sciences, Winston-Salem
Се регрутираФаза 1
Возраст од 18 до 75 · Сите полови · Ажурирано 25.8.2026 · NCT05886049

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

  • University of North Carolina, Chapel Hill, Chapel Hill
  • Duke University Medical Center, Durham
Се регрутираФаза 3
Возраст 18 и постари · Сите полови · Ажурирано 20.8.2026 · NCT07007312

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

  • Atrium Health Levine Cancer Center, Charlotte
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 20.8.2026 · NCT06001788

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

  • University of North Carolina at Chapel Hill, Chapel Hill
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 18.8.2026 · NCT06656494

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

  • Levine Cancer Institute, Charlotte
  • Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Се регрутираНабљудувачка студија
Возраст 18 и постари · Сите полови · Ажурирано 24.7.2026 · NCT06580106

ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

  • Levine Cancer Insitute, Charlotte
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Се регрутира
Возраст од 18 до 64 · Сите полови · Ажурирано 23.7.2026 · NCT06945042

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

  • Research Site, Chapel Hill
  • Research Site, Durham
Се регрутираФаза 1/2
Возраст 16 и постари · Сите полови · Ажурирано 20.7.2026 · NCT07155226

Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

  • University of North Carolina at Chapel Hill, Chapel Hill
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 10.7.2026 · NCT05442216

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

  • University of North Carolina at Chapel Hill, Chapel Hill
  • Levine Children's Hospital, Charlotte
  • Duke University Medical Center, Durham
Се регрутираНабљудувачка студија
Сите возрасти · Сите полови · Ажурирано 6.7.2026 · NCT01351545

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

  • University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Section of Hematology/Oncology, Winston-Salem
Се регрутира
Возраст 60 и постари · Сите полови · Ажурирано 6.7.2026 · NCT06697600

Registry of Older Patients With Cancer

  • Seby B. Jones Cancer Center, Boone
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
  • East Carolina University, Greenville
  • и уште 4
Се регрутираНабљудувачка студија
Возраст 65 и постари · Сите полови · Ажурирано 29.6.2026 · NCT01137825

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

  • UNC Hospitals, University of North Carolina at Chapel Hill, Chapel Hill
Се регрутираФаза 2
Возраст 18 и постари · Сите полови · Ажурирано 23.6.2026 · NCT05401097

A Study of Revumenib and Mezigdomide in People With Leukemia

  • University of North Carolina (Data Collection Only), Chapel Hill
Се регрутираФаза 1/2
Возраст 12 и постари · Сите полови · Ажурирано 22.6.2026 · NCT07356154

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

  • UNC Hospitals, University of North Carolina at Chapel Hill, Chapel Hill
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 14.5.2026 · NCT06222580

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

  • University of North Carolina, Chapel Hill
Се регрутираФаза 1
Возраст 13 и постари · Сите полови · Ажурирано 5.5.2026 · NCT04771572

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • Duke University, Durham
Се регрутираФаза 2/3
Возраст 18 и постари · Сите полови · Ажурирано 30.4.2026 · NCT04256317

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

  • Wake Forest Baptist Health, Winston-Salem
Се регрутираНабљудувачка студија
Возраст од 18 до 120 · Сите полови · Ажурирано 13.4.2026 · NCT01890486

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

  • UNC Hospital, Chapel Hill
  • Duke University, Durham
  • Atrium Wake Forest Baptist Medical Center, Winston-Salem
Се регрутираФаза 1/2
Возраст 12 и постари · Сите полови · Ажурирано 24.3.2026 · NCT04988555

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

  • University of North Carolina, Chapel Hill
Се регрутираФаза 2
Возраст од 18 до 66 · Сите полови · Ажурирано 17.3.2026 · NCT06859424

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

  • Duke Blood Cancer Center, Durham
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 13.3.2026 · NCT05735184

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

  • Duke Cancer Center, Durham
Се регрутираФаза 1
Возраст 18 и постари · Сите полови · Ажурирано 16.1.2026 · NCT05143996

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

  • Novant Health Cancer Institute, Charlotte
  • Novant Health Cancer Institute, Winston-Salem
Се регрутираФаза 1/2
Возраст 18 и постари · Сите полови · Ажурирано 10.12.2025 · NCT06680752

Novel Digital Application for Patients With Acute Leukemia

  • Duke University, Durham
Се регрутира
Возраст од 18 до 120 · Сите полови · Ажурирано 10.11.2025 · NCT06472128

Од ClinicalTrials.gov, податоци преземени 6.10.2026. Секоја студија ги поставува своите услови за вклучување; тимот на студијата одлучува кој може да учествува.