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Insomnia clinical trials recruiting in the U.S.
108 studies for Insomnia are recruiting participants at sites across the United States.
Cities with the most studies
- Boston, MA11 studies
- Houston, TX5 studies
- Atlanta, GA5 studies
- Baltimore, MD5 studies
- Tampa, FL5 studies
- Los Angeles, CA4 studies
- Columbia, MO4 studies
- Chicago, IL4 studies
- Durham, NC3 studies
- Detroit, MI3 studies
- San Francisco, CA3 studies
- Winston-Salem, NC3 studies
- Philadelphia, PA3 studies
- Providence, RI3 studies
- Charleston, SC3 studies
- Denver, CO3 studies
- St. Louis, MO3 studies
- Tallahassee, FL3 studies
- Farmington Hills, MI3 studies
- San Antonio, TX3 studies
- Mountain View, CA3 studies
- Washington, DC3 studies
- Miami, FL3 studies
By state
- Arizona4 studies
- California19 studies
- Colorado6 studies
- Florida15 studies
- Georgia7 studies
- Illinois5 studies
- Indiana3 studies
- Maryland6 studies
- Massachusetts13 studies
- Michigan8 studies
- Missouri8 studies
- Nevada3 studies
- New Jersey3 studies
- New York4 studies
- North Carolina9 studies
- Ohio5 studies
- Pennsylvania7 studies
- Rhode Island3 studies
- South Carolina4 studies
- Texas12 studies
- Virginia5 studies
- Washington3 studies
Recently updated studies
Deep Sleep in Older Adults
RecruitingPhase 2
Ages 55 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT07316153The Impact of Overnight Active Temperature Regulation on Gut Microbiome, Inflammation, and Circadian Rhythm.
RecruitingHealthy volunteers welcome
Ages 45 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07848594Insomnia and Insulin Resistance
RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT07333586Benefits of Nicotinamide Riboside Upon Cognition and Sleep
RecruitingHealthy volunteers welcome
Ages 65 to 85 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT05500170Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
Recruiting
Ages 45 to 60 ยท Women ยท Updated Sep 22, 2026 ยท NCT07834463A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06655883A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia
RecruitingPhase 4
Ages 18 to 80 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07542756Almonds, Gut Microbiome and Kids
RecruitingHealthy volunteers welcome
Ages 6 to 13 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07636850Sleep as a Mechanism of Change in Alcohol Use
RecruitingHealthy volunteers welcome
Ages 18 to 49 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT06286774Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
Recruiting
Ages 65 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT06375265Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr
Recruiting
Ages 6 to 12 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07091149Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women
Recruiting
Ages 45 to 65 ยท Women ยท Updated Sep 11, 2026 ยท NCT07751029A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children
RecruitingHealthy volunteers welcome
Ages 11 to 13 ยท All sexes ยท Updated Sep 4, 2026 ยท NCT06942455Enhancing Diabetes Care by Treating Insomnia
Recruiting
Ages 40 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07062406Piloting an Insomnia Treatment in Patients With Ulcerative Colitis
Recruiting
Ages 18 and older ยท All sexes ยท Updated Aug 28, 2026 ยท NCT07428629Smart Pillows for Enhancing Sleep Quality
Recruiting
Ages 50 and older ยท All sexes ยท Updated Aug 21, 2026 ยท NCT06594627Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 ยท All sexes ยท Updated Aug 21, 2026 ยท NCT04278404Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia
Recruiting
Ages 20 to 50 ยท All sexes ยท Updated Aug 14, 2026 ยท NCT07191119Multi-center Trial to Improve Nocturia and Sleep in Older Adults
Recruiting
Ages 60 and older ยท All sexes ยท Updated Aug 13, 2026 ยท NCT06110091Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga
RecruitingHealthy volunteers welcome
Ages 18 to 40 ยท All sexes ยท Updated Aug 13, 2026 ยท NCT07638267Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients
RecruitingPhase 3
Ages 18 to 65 ยท All sexes ยท Updated Jul 30, 2026 ยท NCT07336277Affect of Melatonin on Sleep and Cognition in Cirrhosis
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 29, 2026 ยท NCT07046429Treatments for Insomnia in Veterans With PTSD
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 27, 2026 ยท NCT05194930Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
RecruitingPhase 3
Ages 18 to 65 ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06568367Comparing Acoustic Resonance Therapy (ART) vs. Cognitive Behavioral Therapy for Insomnia (CBT-I)
Recruiting
Ages 22 and older ยท All sexes ยท Updated Jul 20, 2026 ยท NCT07486882From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.