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Metastatic Cancer clinical trials in Colorado
50 studies for Metastatic Cancer are looking for participants at sites in Colorado.
Cities in Colorado
- Denver29 studies
- Aurora25 studies
- Centennial5 studies
- Grand Junction3 studies
- Highlands Ranch3 studies
- Loveland3 studies
- Greeley3 studies
- Fort Collins3 studies
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
- UCHealth University of Colorado Hospital, Aurora
- Poudre Valley Hospital, Fort Collins
- Cancer Care and Hematology-Fort Collins, Fort Collins
- and 2 more
RecruitingPhase 2
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Rocky Mountain Cancer Center, Denver
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
- Sarah Cannon Research Institute at HealthOne, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
- Poudre Valley Health Care, Inc, Fort Collins
- Rocky Mountain Cancer Centers, Lone Tree
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
- University of Colorado Anschutz Medical Campus, Aurora
- Rocky Mountain Cancer Centers, LLP, Lone Tree
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
- SCRI at HealthOne, Denver
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957A Study of ASP3082 in Adults With Advanced Solid Tumors
- Denver HealthONE Drug Development Unit, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
- Rocky Mountain Cancer Centers, LLP, Aurora
- Rocky Mountain Cancer Centers - Boulder, Boulder
- Rocky Mountain Cancer Centers, LLP, Centennial
- and 18 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
- Children's Hospital Colorado - Anschutz Medical Campus, Aurora
RecruitingPhase 1/2
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
- Research Site, Aurora
- Research Site, Denver
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06103864ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
- Saint Joseph Hospital - Cancer Centers of Colorado, Denver
- Lutheran Hospital - Cancer Centers of Colorado, Golden
- Saint Mary's Regional Hospital - Cancer Centers of Colorado, Grand Junction
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
- University of Colorado Cancer Center, Denver
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
- AdventHealth Medical Group - Porter, Denver
- Colorado West Healthcare System - Grand Valley Oncology, Grand Junction
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
- UCHealth Harmony, Fort Collins
- Cancer Centers of Colorado St. Mary's Regional Hospital, Grand Junction
- Banner MD Anderson Cancer Center at North Colorado Medical Center, Greeley
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
- Anschutz Cancer Pavilion, Aurora
- AdventHealth Medical Group - Porter, Denver
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
- Rocky Mountain Cancer Centers,LLP, Aurora
- Clinical and Translational Research Center(CTRC), Aurora
- University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP), Aurora
- and 8 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415Study of ISM6331 in Participants With Advanced/Metastatic Mesothelioma or Other Advanced Solid Tumors
- Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06566079CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
- Clinical Study Site, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07335497A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- USO - Rocky Mountain Cancer Centers, Lone Tree
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
- University of Colorado Health Hospital, Aurora
- Sarah Cannon Research Institute at HealthOne, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
- Avenzo Therapeutics Recruiting Site, Denver
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
- Sarah Cannon Research Institute Denver, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
- University of Colorado, Aurora
RecruitingPhase 1
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
- Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)
- Avenzo Therapeutics Recruiting Site, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07193511FOG-001 in Locally Advanced or Metastatic Solid Tumors
- University of Colorado, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors
- Crinetics Study Site, Aurora
- Crinetics Study Site, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07129252A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
- Rocky Mountain Cancer Center, Denver
- Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
- University of Colorado - Aurora Cancer Center, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
- University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Jul 14, 2026 · NCT05533697A Study of PYX-201 in Advanced Solid Tumors
- SCRI - HealthOne Denver, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT05720117CT-95 in Advanced Cancers Associated With Mesothelin Expression
- Context Investigational Site, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06756035A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
- University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT05384626Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
- UCHealth Memorial Hospital Central, Colorado Springs
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06697301Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma
- University of Colorado Hospital - Anschutz Cancer Pavilion, Aurora
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06947928A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
- University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06362369A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
- University of Colorado Hospital - Anschutz Cancer Pavilion(ACP), Aurora
- The Melanoma & Skin Cancer Institute, Englewood
RecruitingPhase 2/3
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
- Sarah Cannon Research Institute (SCRI) at HealthONE, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05948865Venetoclax Basket Trial for High Risk Hematologic Malignancies
- Children's Hospital Colorado, Aurora
RecruitingPhase 1
Ages 1 to 40 · All sexes · Updated Mar 12, 2026 · NCT05292664From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.