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Metastatic Cancer clinical trials in New York

111 studies for Metastatic Cancer are looking for participants at sites in New York.

Cities in New York

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

  • Roswell Park Cancer Institute, Buffalo
  • Memorial Sloan Kettering Commack, Commack
  • Memorial Sloan Kettering Westchester, Harrison
  • and 8 more
RecruitingPhase 2
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering, New York
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • Icahn School of Medicine at Mount Sinai, New York
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

  • START New York Long Island LLC, Lake Success
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

  • Research Site, New York
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07205822

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma

  • Roswell Park Comprehensive, Buffalo
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05287945

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of ASP3082 in Adults With Advanced Solid Tumors

  • Roswell Park Cancer Institute, Buffalo
  • Columbia University - Herbert Irving Comprehensive Cancer Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

  • Roswell Park Cancer Institute, Buffalo
  • Icahan School of Medicine at Mount Sinai, New York
  • University of Rochester Medical Center, Rochester
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

  • Montefiore Medical Center-Einstein Campus, The Bronx
  • Montefiore Medical Center-Weiler Hospital, The Bronx
  • Montefiore Medical Center - Moses Campus, The Bronx
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05803382

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • NYOH Albany Cancer Center, Albany
  • Hematology-Oncology Associates of Central New York, PC, Auburn
  • North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists, Babylon
  • and 12 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • Columbia University Irving Medical Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

  • New York Oncology Hematology, Albany
  • New York Oncology Hematology, Clifton Park
  • Hematology Oncology Associates of Rockland, Nyack
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • Icahn School of Medicine at Mount Sinai, New York
  • University of Rochester Medical Center, Rochester
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07612176

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789

A Study of ZEN003694 in People With Squamous Cell Lung Cancer

  • Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities ), Commack
  • Memorial Sloan Kettering Westchester (All Protocol Activities), East White Plains
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05607108

Intratumoral N17350 in Advanced Solid Tumors

  • Roswell Park Comprehensive Cancer Center, Buffalo
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

  • Columbia University Irving Medical Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • Weill Cornell Medical College, New York
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

  • NYOH Albany Cancer Center, Albany
  • New York University (NYU) Brooklyn, Brooklyn
  • Memorial Sloan Kettering Cancer Center, New York
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Columbia University, New York
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • New York University (NYU) Langone Medical Center, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

  • START New York-Long Island, Lake Success
  • Memorial Sloan Kettering Cancer Center (MSKCC), New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07262619

SLV-154 Treatment of Advanced Cancers

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT06771219

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

  • Roswell Park Cancer Institute, Buffalo
  • Northwell Health/ RJ Zuckerberg Cancer Center, Lake Success
  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island, Mineola
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • NYU Langone Health Perlmutter Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

  • Memorial Sloan Kettering Cancer Center - Main Campus, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07450859

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

  • New York Oncology Hematology, P.C., Albany
  • New York Oncology Hematology - Clifton Park Cancer Center, Clifton Park
  • MSK Commack, Commack
  • and 7 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

  • Memorial Sloan Kettering Cancer Center ( Site 0006), New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06863272

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

  • Tisch Cancer Institute (TCI), Icahn School of Medicine, New York
  • Columbia University, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04977453

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

  • Clinical Study Site, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07335497

NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies

  • Montefiore, The Bronx
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Sep 8, 2026 · NCT07563829

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Maimonides Cancer Center, Brooklyn
  • Northwell Health/ RJ Zuckerberg Cancer Center, Lake Success
  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island, Mineola
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06311214

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.