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Treatment-Resistant Depressive Disorder clinical trials in Illinois

4 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Illinois.

Cities in Illinois

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

  • Psychiatric Medicine Associates LLC, Skokie
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07716098

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

  • Rush University Medical Center, Chicago
Recruiting
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • Rush University Medical Center, Chicago
  • AMR- Baber Research, Inc., Naperville
  • Psychiatric Medicine Associates, LLC, Skokie
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

  • Pillar Clinical Research LLC, Chicago
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.