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Small Cell Lung Cancer clinical trials in California

36 studies for Small Cell Lung Cancer are looking for participants at sites in California.

Cities in California

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of San Diego Moores Cancer Center, La Jolla
  • UCLA Jonsson Comprehensive Cancer Center, Los Angeles
  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • University of California - Los Angeles, Los Angeles
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

  • City of Hope National Medical Center, Duarte
  • UC San Diego Medical Center - Encinitas, Encinitas
  • City of Hope Lennar Foundation Cancer Center, Irvine
  • and 9 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07476287

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]

  • GSK Investigational Site, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07099898

DESTINY-PANTUMOUR04

  • Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

  • Kivu Trial Site, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07229313

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

  • Precision NextGen Oncology, Beverly Hills
  • OPN Healthcare, Inc, Glendale
  • University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

  • City of Hope National Medical Center /ID# 281322, Duarte
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 281396, Irvine
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

  • START Los Angeles, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Beverly Hills Cancer Center, Beverly Hills
  • City of Hope Cancer Center, Duarte
  • University of California Irvine Medical Center, Orange
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

  • Valkyrie Clinical Trials, Inc., Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07459634

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

  • Los Alamitos Hematology/Oncology Medical Group, Glendale
  • MemorialCare Todd Cancer Institute, Long Beach
  • Valkyrie Clinical Trials, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07625644

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

  • University of California San Diego, La Jolla
  • UC Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07218146

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, Los Angeles
  • Avenzo Therapeutics Recruiting Site, Los Angeles
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

  • University of California LA, Los Angeles
RecruitingPhase 1/2
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT06726148

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

  • Precision NextGen Oncology and Research Center, Beverly Hills
  • Cedars Sinai Medical Center, Los Angeles
  • UCLA - David Geffen School of Medicine, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06892548

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

  • University of Southern California, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06922539

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

  • The Oncology Institute of Hope and Innovation, Long Beach
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06095505

A Study of MGC026 in Participants With Advanced Solid Tumors

  • The Angeles Clinic and Research Institute, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

  • Clinical Research Providence Medical Foundation, Fullerton
  • UCLA Hematology-Oncology, Los Angeles
  • UCSF Mission Bay Mission Hall, San Francisco
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06203210

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

  • Valkyrie Clinical Trials, Los Angeles
  • University of California San Francisco, San Francisco
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05882058

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte
  • IP Address: City of Hope Investigational Drug Services(IDS), Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte
  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT05652686

LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)

  • University of California, Davis, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT06103682

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

  • University of Southern California, Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06598306

A Study of LY4175408 in Participants With Advanced Cancer

  • Stanford Medicine Cancer Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

  • Start Lacn, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07517198

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

  • Beckman Research Institute of City of Hope, Duarte
  • VA Medical Center, Fresno, Fresno
  • Santa Clara Valley Medical Center, Fruitdale
  • and 5 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

  • Loma Linda University Medical Center, Loma Linda
  • Eisenhower Medical Center, Rancho Mirage
  • University of California Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06769126

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06681220

Engagement of Veterans With Lung Cancer

  • Veterans Affairs Palo Alto Health Care System (VAPAHCS), Palo Alto
Recruiting
Ages 18 and older · All sexes · Updated Mar 3, 2026 · NCT07219251

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Providence Medical Foundation (site 209), Santa Rosa
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 125, Los Angeles
  • Research Site 133, Los Angeles
  • Research Site 103, Los Angeles
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

  • Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles
RecruitingPhase 2
All ages · All sexes · Updated Nov 17, 2025 · NCT05588388

A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer

  • Zelgen Site 105, Orange
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Aug 6, 2025 · NCT06592638

A Multicenter Cancer Biospecimen Collection Study

  • Curebase, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2025 · NCT04510129

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.