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Kliniske studier for Kronisk lymfatisk leukemi i North Carolina

34 studier for Kronisk lymfatisk leukemi søker deltakere på steder i North Carolina.

Byer i North Carolina

Offisiell studietekst (engelsk)

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Duke University Medical Center, Durham
  • Margaret R Pardee Memorial Hospital, Hendersonville
RekruttererFase 3
Alder 65 og eldre · Alle kjønn · Oppdatert 2. okt. 2026 · NCT07321652

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • AdventHealth Infusion Center Asheville, Asheville
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • AdventHealth Infusion Center Haywood, Clyde
  • og 6 flere
RekruttererObservasjonsstudieFrivillige helsepersonell ønskes velkommen
Alder 40 til 75 · Alle kjønn · Oppdatert 2. okt. 2026 · NCT05334069

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

  • Research Site, Charlotte
  • Research Site, Winston-Salem
RekruttererFase 1/2
Alder 18 og eldre · Alle kjønn · Oppdatert 30. sep. 2026 · NCT06542250

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • Southeastern Medical Oncology Center-Goldsboro, Goldsboro
  • og 5 flere
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 30. sep. 2026 · NCT04269902

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

  • GC2202 Study Site 109, Greenville
  • GC2202 Decentralized Study Site 114, Morrisville
  • GC2202 Study Site 117, Wilson
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 30. sep. 2026 · NCT05645107

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

  • University of North Carolina At Chapel Hill, Chapel Hill
  • Levine Cancer Center, Charlotte
  • Atrium Health Wake Forest Baptist, Winston-Salem
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 28. sep. 2026 · NCT06943872

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

  • Atrium Health Levine Cancer Institute (Lci), Charlotte
  • Duke University Medical Center, Durham
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 28. sep. 2026 · NCT07277231

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  • University of North Carolina At Chapel Hill, Chapel Hill
  • Atrium Health Levine Cancer Institute (Lci), Charlotte
  • Duke University Medical Center, Durham
  • og 1 flere
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 28. sep. 2026 · NCT06973187

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

  • Carolina Oncology Specialists, PA ( Site 0054), Charlotte
  • Southeastern Medical Oncology Center ( Site 0049), Goldsboro
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 24. sep. 2026 · NCT06136559

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

  • Duke University, Durham
  • Novant Health Cancer Institute, Winston-Salem
RekruttererFase 2
Alder 18 og eldre · Alle kjønn · Oppdatert 17. sep. 2026 · NCT07221500

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
RekruttererFase 2
Alder 18 og eldre · Alle kjønn · Oppdatert 11. sep. 2026 · NCT07061951

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

  • Research Site, Charlotte
  • Research Site, Charlotte
RekruttererFase 1/2
Alder 18 og eldre · Alle kjønn · Oppdatert 8. sep. 2026 · NCT06564038

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

  • UNC School of Medicine, Division of Hematology, Chapel Hill
RekruttererFase 1/2
Alder 12 og eldre · Alle kjønn · Oppdatert 3. sep. 2026 · NCT04588922

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

  • University of North Carolina at Chapel Hill/ University of North Carolina Medical Center, Chapel Hill
RekruttererFase 1/2
Alder 13 til 90 · Alle kjønn · Oppdatert 6. aug. 2026 · NCT06533579

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

  • Research Site, Charlotte
  • Research Site, Durham
  • Research Site, Winston-Salem
RekruttererFase 2
Alder 18 til 130 · Alle kjønn · Oppdatert 6. aug. 2026 · NCT07024706

A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

  • University of North Carolina at Chapel Hill, Chapel Hill
RekruttererFase 1
Alder 18 og eldre · Alle kjønn · Oppdatert 31. jul. 2026 · NCT06708897

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

  • Duke University Medical Center, Durham
RekruttererFase 1
Alder 18 og eldre · Alle kjønn · Oppdatert 2. jul. 2026 · NCT05131022

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

  • North Carolina Basnight Cancer Hospital, Chapel Hill
Rekrutterer
Alder 18 og eldre · Alle kjønn · Oppdatert 1. jul. 2026 · NCT06860880

Registry of Older Patients With Cancer

  • Seby B. Jones Cancer Center, Boone
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
  • East Carolina University, Greenville
  • og 4 flere
RekruttererObservasjonsstudie
Alder 65 og eldre · Alle kjønn · Oppdatert 29. jun. 2026 · NCT01137825

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

  • East Carolina University, Greenville
RekruttererFase 2
Alder 18 og eldre · Alle kjønn · Oppdatert 19. mai 2026 · NCT06588478

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

  • University of North Carolina, Chapel Hill
RekruttererFase 1
Alder 13 og eldre · Alle kjønn · Oppdatert 5. mai 2026 · NCT04771572

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

  • Wake Forest Baptist Health, Winston-Salem
RekruttererObservasjonsstudie
Alder 18 til 120 · Alle kjønn · Oppdatert 13. apr. 2026 · NCT01890486

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

  • Atrium Health /ID# 267219, Charlotte
  • Atrium Health Wake Forest Baptist Medical Center /ID# 273142, Winston-Salem
RekruttererFase 3
Alder 18 og eldre · Alle kjønn · Oppdatert 9. apr. 2026 · NCT06428019

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

  • Duke University Medical Center, Durham
RekruttererFase 4
Alder 18 og eldre · Alle kjønn · Oppdatert 2. mar. 2026 · NCT06876662

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

  • Duke University Medical Center, Durham
RekruttererFase 4
Alder 18 og eldre · Alle kjønn · Oppdatert 2. mar. 2026 · NCT06876649

Study of SGR-1505 in Mature B-Cell Neoplasms

  • Duke University, Durham
RekruttererFase 1
Alder 18 og eldre · Alle kjønn · Oppdatert 13. feb. 2026 · NCT05544019

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

  • University of North Carolina /ID# 233313, Chapel Hill
  • Novant Health Presbyterian Medical Center /ID# 230201, Charlotte
  • Novant Health Forsyth Medical Center /ID# 249533, Winston-Salem
RekruttererFase 2
Alder 18 og eldre · Alle kjønn · Oppdatert 9. feb. 2026 · NCT04895436

Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

  • The University of North Carolina at Chapel Hill, Chapel Hill
RekruttererFase 2
Alder 18 og eldre · Alle kjønn · Oppdatert 7. jan. 2026 · NCT06043674

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

  • Duke University, Durham
RekruttererFase 1
Alder 18 og eldre · Alle kjønn · Oppdatert 10. des. 2025 · NCT05602363

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
RekruttererObservasjonsstudie
Alder 18 til 120 · Alle kjønn · Oppdatert 27. okt. 2025 · NCT01137643

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

  • Durham VA Medical Center, Durham, NC, Durham
RekruttererFase 2
Alder 18 til 80 · Alle kjønn · Oppdatert 14. okt. 2025 · NCT06520098

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

  • University of North Carolina, Chapel Hill
RekruttererFase 1
Alder 18 og eldre · Alle kjønn · Oppdatert 2. okt. 2025 · NCT05780034

CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia

  • Duke University, Durham
RekruttererFase 1
Alder 18 og eldre · Alle kjønn · Oppdatert 17. jul. 2025 · NCT04704323

Fra ClinicalTrials.gov, data hentet 5. okt. 2026. Hver studie setter sine egne kvalifikasjonskrav; studieteamet avgjør hvem som kan delta.