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Ensaios clínicos de Câncer Colorretal em Pensilvânia

69 estudos para Câncer Colorretal estão buscando participantes em locais em Pensilvânia.

Cidades em Pensilvânia

Texto oficial do estudo (Inglês)

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

  • Christiana Care Health System-Concord Health Center, Chadds Ford
  • Geisinger Medical Center, Danville
  • Penn State Milton S Hershey Medical Center, Hershey
  • e mais 4
RecrutandoFase 2
Idades 18 e acima · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT05673148

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
  • University of Pittsburgh Medical Center, Pittsburgh
  • WellSpan York Cancer Center, York
RecrutandoFase 1/2
Idades 12 e acima · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT04585750

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • Lehigh Valley Hospital - Muhlenberg, Bethlehem
  • Geisinger Medical Center, Danville
  • e mais 7
RecrutandoEstudo observacionalVoluntários saudáveis bem-vindos
Idades de 40 a 75 · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT05334069

Family Communications After Genetic Testing

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • Lehigh Valley Hospital - Muhlenberg, Bethlehem
  • Pocono Medical Center, East Stroudsburg
  • e mais 2
RecrutandoVoluntários saudáveis bem-vindos
Idades 18 e acima · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT07143487

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #104, Hershey
  • Exelixis Clinical Site #98, Philadelphia
  • Exelixis Clinical Site #32, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 1 de out. de 2026 · NCT05176483

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

  • Penn State Milton S. Hershey Medical Center, Hershey
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 30 de set. de 2026 · NCT06324357

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 29 de set. de 2026 · NCT05877599

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 29 de set. de 2026 · NCT05803382

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

  • GSK Investigational Site, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT07277270

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

  • Research Site, Philadelphia
  • Research Site, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT06218914

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

  • Alliance Cancer Specialists at Main Line, Penn Wynne
  • Thomas Jefferson University, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
  • e mais 1
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT06750094

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

  • Thomas Jefferson University, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
  • University Of Pittsburgh Medical Center UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT06662786

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • Saint Vincent Hospital, Erie
  • Jefferson Hospital, Jefferson Hills
  • e mais 5
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 24 de set. de 2026 · NCT05863195

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

  • Lehigh Valley Health Network, Allentown
  • Local Institution - 0604, Pittsburgh
RecrutandoFase 2/3
Idades 18 e acima · Todos os sexos · Atualizado em 23 de set. de 2026 · NCT07221357

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Allegheny Health Network, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT06128551

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • University of Pittsburgh Medical Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07114601

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

  • Hospital of the University of Pennsylvania, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT06445062

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • University of Pennsylvania, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07213791

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • Alliance Cancer Specialists, Doylestown
  • Penn State Milton S. Hershey Medical Center, Hershey
  • University of Pennsylvania, Philadelphia
  • e mais 3
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 15 de set. de 2026 · NCT07284849

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 10 de set. de 2026 · NCT07812805

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

  • Clinical Study Site, Lebanon
  • Clinical Study Site, Philadelphia
  • Clinical Study Site, Philadelphia
  • e mais 4
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 8 de set. de 2026 · NCT07228832

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 2 de set. de 2026 · NCT07216105

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

  • UPenn Lancaster-Ann B. Barshinger Cancer Institute, Lancaster
  • Thomas Jefferson University - Sidney Kimmel Comprehensive Cancer Center, Philadelphia
  • UPMC / University of Pittsburgh Medical Center, Pittsburgh
RecrutandoFase 2
Idades 18 e acima · Todos os sexos · Atualizado em 1 de set. de 2026 · NCT06992258

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • Children's Hospital of Philadelphia, Philadelphia
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
RecrutandoFase 1/2
12 Months – 30 Years · Todos os sexos · Atualizado em 25 de ago. de 2026 · NCT04851119

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

  • University of Pittsburgh Medical Center (UPMC) - Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 24 de ago. de 2026 · NCT06586515

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 2
Idades 18 e acima · Todos os sexos · Atualizado em 20 de ago. de 2026 · NCT07235293

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

  • University of Pennsylvania, Philadelphia
RecrutandoEstudo observacional
Idades 18 e acima · Todos os sexos · Atualizado em 18 de ago. de 2026 · NCT05410977

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Pennsylvania, Perelman School of Medicine, Philadelphia
  • University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 17 de ago. de 2026 · NCT05919264

TCR1188-ABC Cells in KRAS-mutated Cancers

  • University of Pennsylvania, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 6 de ago. de 2026 · NCT07594067

Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

  • PennState Health - Milton S. Hershey Medical Center, Hershey
RecrutandoVoluntários saudáveis bem-vindos
Idades de 19 a 80 · Todos os sexos · Atualizado em 5 de ago. de 2026 · NCT05826743

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 31 de jul. de 2026 · NCT05691491

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 31 de jul. de 2026 · NCT06654037

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

  • Thomas Jefferson University, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 30 de jul. de 2026 · NCT07094113

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

  • University of Pennsylvania / Abramson Cancer Center, Philadelphia
  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 30 de jul. de 2026 · NCT04657068

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

  • University of Pennsylvania, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 29 de jul. de 2026 · NCT03526835

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

  • Jefferson University Hospitals, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 22 de jul. de 2026 · NCT06179160

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

  • UPMC Hillman Cancer Center - Beaver, Beaver
  • UPMC Hillman Cancer Center at Butler Health System, Butler
  • UPMC Hillman Cancer Center Erie, Erie
  • e mais 10
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 22 de jul. de 2026 · NCT05253651

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia
RecrutandoFase 2
Idades 18 e acima · Todos os sexos · Atualizado em 16 de jul. de 2026 · NCT06948448

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

  • University of Pittsburg Medical Center _UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 15 de jul. de 2026 · NCT06657144

Fonte: ClinicalTrials.gov, dados obtidos em 5 de out. de 2026. Cada estudo define seus próprios critérios de elegibilidade; a equipe do estudo decide quem pode participar.