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Ensaios clínicos de Câncer de Pulmão de Não Pequenas Células em Kentucky

47 estudos para Câncer de Pulmão de Não Pequenas Células estão buscando participantes em locais em Kentucky.

Cidades em Kentucky

Texto oficial do estudo (Inglês)

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Baptist Health Hardin, Elizabethtown
Baptist Health Lexington, Lexington
Baptist Health Hamburg, Lexington
e mais 2

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 30 de set. de 2026 · NCT04267848

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

University of Kentucky Chandler Medical Center, Lexington

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 30 de set. de 2026 · NCT07361497

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

Owensboro Health Mitchell Memorial Cancer Center, Owensboro

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 29 de set. de 2026 · NCT07388524

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Norton Cancer Institute Downtown, Louisville
Norton Cancer Institute, Downtown, Louisville
Norton Hospital, Louisville
e mais 4

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 28 de set. de 2026 · NCT07144280

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

Research Site, Lexington
Research Site, Owensboro

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT06868277

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0061), Edgewood

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT06312137

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

Baptist Health Lexington, Lexington
Baptist Health Hamburg, Lexington

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 24 de set. de 2026 · NCT06890598

Pan-tumor MRD Study

Baptist Health Corbin, Corbin
Baptist Health Hardin, Elizabethtown
Baptist Health Lexington, Lexington
e mais 1

RecrutandoEstudo observacional

Idades 18 e acima · Todos os sexos · Atualizado em 24 de set. de 2026 · NCT06605404

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Research Site, Paducah

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 23 de set. de 2026 · NCT06357533

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Saint Elizabeth Medical Center Edgewood, Edgewood
Baptist Health Lexington, Lexington
Local Institution - 0502, Paducah

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 23 de set. de 2026 · NCT06561386

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Baptist Health Hardin, Elizabethtown
Baptist Health Lexington, Lexington
University of Kentucky Chandler Medical Center (UKCMC) - Markey Cancer Center (Lucille P. Markey Cancer Center), Lexington

RecrutandoFase 2/3

Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT06712316

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

Saint Elizabeth Medical Center Edgewood, Edgewood
The University of Louisville, James Graham Brown Cancer Center, Louisville
Owensboro Medical Health System, Owensboro
e mais 1

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT06875310

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

Norton Cancer Institute, Louisville

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 21 de set. de 2026 · NCT05983432

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Research Site, Lexington
Research Site, Louisville
Research Site, Louisville

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 18 de set. de 2026 · NCT06692738

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

Clinical Study Site, Lexington

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 18 de set. de 2026 · NCT06767514

A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Local Institution - 0034, Lexington
Local Institution - 0171, Lexington

RecrutandoFase 2

Idades 18 e acima · Todos os sexos · Atualizado em 16 de set. de 2026 · NCT07680764

Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

Markey Cancer Center, Lexington

RecrutandoFase 1/2

Idades 18 e acima · Todos os sexos · Atualizado em 16 de set. de 2026 · NCT04486833

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Lexington Medical Cancer Center Hematology/Oncology, Lexington
University of Louisville, Louisville
Local Institution - 007-388-A, Louisville

RecrutandoFase 2/3

Idades 18 e acima · Todos os sexos · Atualizado em 16 de set. de 2026 · NCT04613596

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Baptist Health Lexington /ID# 261823, Lexington

RecrutandoFase 2/3

Idades 18 e acima · Todos os sexos · Atualizado em 14 de set. de 2026 · NCT06236438

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Norton Cancer Institute Research, Louisville

RecrutandoFase 1/2

Idades 18 e acima · Todos os sexos · Atualizado em 14 de set. de 2026 · NCT06303505

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

Norton Cancer Institute PARENT, Louisville

RecrutandoFase 1/2

Idades 18 e acima · Todos os sexos · Atualizado em 9 de set. de 2026 · NCT06750185

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

CHI Saint Joseph Cancer Center - East, Lexington
University of Kentucky Chandler Medical Center, Lexington

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 8 de set. de 2026 · NCT06119581

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

Research Site, Louisville

RecrutandoFase 3

Idades 18 e acima · Todos os sexos · Atualizado em 4 de set. de 2026 · NCT07291037

A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

University of Kentucky Chandler Medical Center ( Site 0019), Lexington

RecrutandoFase 2

Idades 18 e acima · Todos os sexos · Atualizado em 25 de ago. de 2026 · NCT06780085

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

St. Elizabeth Healthcare, Edgewood

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 21 de ago. de 2026 · NCT06774963

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

University of Kentucky ( Site 0019), Lexington

RecrutandoFase 2

Idades 18 e acima · Todos os sexos · Atualizado em 18 de ago. de 2026 · NCT06731907

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

Exelixis Clinical Site #122, Louisville

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 5 de ago. de 2026 · NCT05176483

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Norton Cancer Institute, Louisville

RecrutandoFase 1/2

Idades 18 e acima · Todos os sexos · Atualizado em 29 de jul. de 2026 · NCT04198766

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

University of Kentucky Chandler Medical Center, Lexington
Norton Cancer Institute, Louisville

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 22 de jul. de 2026 · NCT05142189

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

James Graham Brown Cancer Center (Melanoma/NSCLC), Louisville

RecrutandoFase 1/2

Idades 18 e acima · Todos os sexos · Atualizado em 16 de jul. de 2026 · NCT06060613

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

University of Louisville, Louisville

RecrutandoFase 2

Idades de 18 a 70 · Todos os sexos · Atualizado em 26 de jun. de 2026 · NCT04614103

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Norton Cancer Institute /ID# 248903, Louisville

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 23 de jun. de 2026 · NCT05005403

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

University of Louisville, Louisville

RecrutandoFase 1/2

Idades de 18 a 70 · Todos os sexos · Atualizado em 11 de jun. de 2026 · NCT05361174

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

UK Markey Cancer Center, Lexington

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 11 de jun. de 2026 · NCT05283330

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

University of Kentucky/Markey Cancer Center, Lexington

RecrutandoFase 2

Idades 18 e acima · Todos os sexos · Atualizado em 3 de jun. de 2026 · NCT05642572

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Research Site, Louisville

RecrutandoFase 3

Idades de 18 a 130 · Todos os sexos · Atualizado em 14 de mai. de 2026 · NCT06417814

A Study of ZW251 in Participants With Advanced Solid Tumors

Norton Cancer Institute, Louisville

RecrutandoFase 1

Idades 18 e acima · Todos os sexos · Atualizado em 7 de mai. de 2026 · NCT07164313

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

University of Kentucky/Markey Cancer Center, Lexington

RecrutandoFase 2

Idades 18 e acima · Todos os sexos · Atualizado em 6 de mai. de 2026 · NCT06116682

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

University of Kentucky/Markey Cancer Center, Lexington

RecrutandoFase 2/3

Idades 18 e acima · Todos os sexos · Atualizado em 5 de mai. de 2026 · NCT06616584

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

University of Kentucky/Markey Cancer Center, Lexington

RecrutandoFase 2

18 Minutes · Todos os sexos · Atualizado em 5 de mai. de 2026 · NCT06031688

Fonte: ClinicalTrials.gov, dados obtidos em 1 de out. de 2026. Cada estudo define seus próprios critérios de elegibilidade; a equipe do estudo decide quem pode participar.