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Klinične študije za Nemalicelični pljučni rak v Kentucky

46 študij za Nemalicelični pljučni rak išče udeležence na lokacijah v Kentucky.

Mesta v Kentucky

Uradno besedilo študije (angleško)

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

  • Baptist Health Corbin, Corbin
  • Baptist Health Hardin, Elizabethtown
  • Baptist Health Lexington, Lexington
  • in še 3
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 2. okt. 2026 · NCT04267848

A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

  • University of Kentucky Chandler Medical Center ( Site 0019), Lexington
Vključevanje udeležencevFaza 2
Starost 18 in več · Vsi spoli · Posodobljeno 1. okt. 2026 · NCT06780085

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

  • Owensboro Health Mitchell Memorial Cancer Center, Owensboro
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 1. okt. 2026 · NCT07388524

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

  • University of Kentucky Chandler Medical Center, Lexington
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 30. sep. 2026 · NCT07361497

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

  • Norton Cancer Institute Downtown, Louisville
  • Norton Cancer Institute, Downtown, Louisville
  • Norton Hospital, Louisville
  • in še 4
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 28. sep. 2026 · NCT07144280

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

  • Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0061), Edgewood
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 25. sep. 2026 · NCT06312137

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

  • Research Site, Lexington
  • Research Site, Owensboro
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 25. sep. 2026 · NCT06868277

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

  • Baptist Health Lexington, Lexington
  • Baptist Health Hamburg, Lexington
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 24. sep. 2026 · NCT06890598

Pan-tumor MRD Study

  • Baptist Health Corbin, Corbin
  • Baptist Health Hardin, Elizabethtown
  • Baptist Health Lexington, Lexington
  • in še 1
Vključevanje udeležencevOpazovalna študija
Starost 18 in več · Vsi spoli · Posodobljeno 24. sep. 2026 · NCT06605404

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

  • Saint Elizabeth Medical Center Edgewood, Edgewood
  • Baptist Health Lexington, Lexington
  • Local Institution - 0502, Paducah
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 23. sep. 2026 · NCT06561386

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

  • Baptist Health Hardin, Elizabethtown
  • Baptist Health Lexington, Lexington
  • University of Kentucky Chandler Medical Center (UKCMC) - Markey Cancer Center (Lucille P. Markey Cancer Center), Lexington
Vključevanje udeležencevFaza 2/3
Starost 18 in več · Vsi spoli · Posodobljeno 22. sep. 2026 · NCT06712316

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

  • Saint Elizabeth Medical Center Edgewood, Edgewood
  • The University of Louisville, James Graham Brown Cancer Center, Louisville
  • Owensboro Medical Health System, Owensboro
  • in še 1
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 22. sep. 2026 · NCT06875310

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Norton Cancer Institute, Louisville
Vključevanje udeležencevFaza 1
Starost 18 in več · Vsi spoli · Posodobljeno 21. sep. 2026 · NCT05983432

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

  • Research Site, Lexington
  • Research Site, Louisville
  • Research Site, Louisville
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 18. sep. 2026 · NCT06692738

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

  • Clinical Study Site, Lexington
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 18. sep. 2026 · NCT06767514

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

  • Lexington Medical Cancer Center Hematology/Oncology, Lexington
  • University of Louisville, Louisville
  • Local Institution - 007-388-A, Louisville
Vključevanje udeležencevFaza 2/3
Starost 18 in več · Vsi spoli · Posodobljeno 16. sep. 2026 · NCT04613596

Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

  • Markey Cancer Center, Lexington
Vključevanje udeležencevFaza 1/2
Starost 18 in več · Vsi spoli · Posodobljeno 16. sep. 2026 · NCT04486833

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

  • Norton Cancer Institute Research, Louisville
Vključevanje udeležencevFaza 1/2
Starost 18 in več · Vsi spoli · Posodobljeno 14. sep. 2026 · NCT06303505

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

  • Norton Cancer Institute PARENT, Louisville
Vključevanje udeležencevFaza 1/2
Starost 18 in več · Vsi spoli · Posodobljeno 9. sep. 2026 · NCT06750185

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • CHI Saint Joseph Cancer Center - East, Lexington
  • University of Kentucky Chandler Medical Center, Lexington
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 8. sep. 2026 · NCT06119581

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

  • Research Site, Louisville
Vključevanje udeležencevFaza 3
Starost 18 in več · Vsi spoli · Posodobljeno 4. sep. 2026 · NCT07291037

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

  • St. Elizabeth Healthcare, Edgewood
Vključevanje udeležencevFaza 1
Starost 18 in več · Vsi spoli · Posodobljeno 21. avg. 2026 · NCT06774963

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

  • University of Kentucky ( Site 0019), Lexington
Vključevanje udeležencevFaza 2
Starost 18 in več · Vsi spoli · Posodobljeno 18. avg. 2026 · NCT06731907

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • Norton Cancer Institute, Louisville
Vključevanje udeležencevFaza 1/2
Starost 18 in več · Vsi spoli · Posodobljeno 29. jul. 2026 · NCT04198766

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

  • University of Kentucky Chandler Medical Center, Lexington
  • Norton Cancer Institute, Louisville
Vključevanje udeležencevFaza 1
Starost 18 in več · Vsi spoli · Posodobljeno 22. jul. 2026 · NCT05142189

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

  • James Graham Brown Cancer Center (Melanoma/NSCLC), Louisville
Vključevanje udeležencevFaza 1/2
Starost 18 in več · Vsi spoli · Posodobljeno 16. jul. 2026 · NCT06060613

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

  • University of Louisville, Louisville
Vključevanje udeležencevFaza 2
Starost 18–70 · Vsi spoli · Posodobljeno 26. jun. 2026 · NCT04614103

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

  • University of Louisville, Louisville
Vključevanje udeležencevFaza 1/2
Starost 18–70 · Vsi spoli · Posodobljeno 11. jun. 2026 · NCT05361174

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

  • UK Markey Cancer Center, Lexington
Vključevanje udeležencevFaza 1
Starost 18 in več · Vsi spoli · Posodobljeno 11. jun. 2026 · NCT05283330

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

  • University of Kentucky/Markey Cancer Center, Lexington
Vključevanje udeležencevFaza 2
Starost 18 in več · Vsi spoli · Posodobljeno 3. jun. 2026 · NCT05642572

A Study of ZW251 in Participants With Advanced Solid Tumors

  • Norton Cancer Institute, Louisville
Vključevanje udeležencevFaza 1
Starost 18 in več · Vsi spoli · Posodobljeno 7. maj 2026 · NCT07164313

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

  • University of Kentucky/Markey Cancer Center, Lexington
Vključevanje udeležencevFaza 2
Starost 18 in več · Vsi spoli · Posodobljeno 6. maj 2026 · NCT06116682

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

  • University of Kentucky/Markey Cancer Center, Lexington
Vključevanje udeležencevFaza 2
18 Minutes · Vsi spoli · Posodobljeno 5. maj 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

  • University of Kentucky/Markey Cancer Center, Lexington
Vključevanje udeležencevFaza 2/3
Starost 18 in več · Vsi spoli · Posodobljeno 5. maj 2026 · NCT06616584

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

  • Baptist Health Hardin, Elizabethtown
Vključevanje udeležencevFaza 2
Starost 18 in več · Vsi spoli · Posodobljeno 24. apr. 2026 · NCT06841055

Vir: ClinicalTrials.gov, podatki pridobljeni 5. okt. 2026. Vsaka študija ima svoje pogoje vključitve; ekipa študije odloči, kdo lahko sodeluje.