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Follow-up Visit of High Risk Infants

RecruitingObservational study

Who can join

18 Months – 26 Months · All sexes

Full eligibility criteria
* Infants inborn at NRN centers
* \<27 weeks gestational age
* Infants enrolled in one or more additional NICHD NRN Follow-up studies. For infants that do not meet the inclusion criteria above, inclusion and exclusion criteria are determined by the criteria for the additional trial(s). In these cases, infants that are larger than 1,000 grams and/or older than 27 weeks may be included in the FU Study.

Note: These inclusion criteria were changed as of 1/1/2008. Prior to this date, infants with birth weights between 401 and 1500 grams who were admitted to NRN NICUs within 14 days of birth were included in the database.

About the study

The NICHD Neonatal Research Network's Follow-Up study is a multi-center cohort in which surviving extremely low birth-weight infants born in participating network centers receive neurodevelopmental, neurosensory and functional assessments at 22-26 months corrected age (Infants born prior to July 1, 2012 were seen at 18-22 months corrected age). Data regarding pregnancy and neonatal outcome are collected prospectively. The goal is to identify potential maternal and neonatal risk factors that may affect infant neurodevelopment.

What is being tested

Sponsor: NICHD Neonatal Research Network · Participants: 68,000 · Started: Apr 1, 1993

Contact the study team

Official record on ClinicalTrials.gov — NCT00009633

Locations in the U.S.

AlabamaUniversity of Alabama at Birmingham, Birmingham
CaliforniaUniversity of California - Los Angeles, Los Angeles
Stanford University, Palo Alto
Sharp Mary Birch Hospital for Women & Newborns, San Diego (Not yet recruiting)
GeorgiaEmory University, Atlanta
IllinoisNorthwestern Lurie Children's Hospital of Chicago, Chicago (Not yet recruiting)
IndianaIndiana University, Indianapolis
IowaUniversity of Iowa, Iowa City
MichiganWayne State University, Detroit
MississippiUniversity of Mississippi Medical Center - Children's of Mississippi, Jackson (Not yet recruiting)
MissouriChildren's Mercy Hospital, Kansas City
New MexicoUniversity of New Mexico, Albuquerque
North CarolinaDuke University, Durham
OhioCincinnati Children's Medical Center, Cincinnati
Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland
PennsylvaniaUniversity of Pennsylvania, Philadelphia
TexasUniversity of Texas Southwestern Medical Center at Dallas, Dallas
University of Texas Health Science Center at Houston, Houston
UtahUniversity of Utah, Salt Lake City

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.