Generic Database of Very Low Birth Weight Infants

RecruitingObservational study

Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants

Who can join

14 Days · All sexes

Full eligibility criteria

Inclusion Criteria:

* Infants inborn at NICHD NRN centers that are:
* 401-1000 grams birth weight, and/or
* 20 0/7 to 28 6/7 weeks (\<29 weeks) gestational age
* Infants enrolled in one or more additional NICHD NRN interventional trials or time-limited observational studies. For infants that do not meet the inclusion criteria above, inclusion and exclusion criteria for the Generic Database are determined by the criteria for the additional trial(s). In these cases, infants that are larger than 1,000 grams and/or older than 29 weeks may be included in the GDB.

Exclusion Criteria:

* Infants \>1,000 grams birth weight and/or \>29 weeks gestational age

Note: These inclusion criteria were changed as of 1/1/2008. Prior to this date, all infants with birth weights between 401 and 1500 grams who are admitted to NRN NICUs within 14 days of birth were included in the database.

About the study

The Generic Database (GDB) is a registry of very low birth weight infants born alive in NICHD Neonatal Research Network (NRN) centers. The GDB collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Data are analyzed to find associations and trends between baseline information, treatments, and infant outcome, and to develop future NRN trials.

What is being tested

No Intervention (other)

Sponsor: NICHD Neonatal Research Network · Participants: 80,000 · Started: Apr 1, 1987

Contact the study team

Ravi M Patal, MD · Phone: 404-727-5905
Abhik Das, PhD · Phone: 301-230-4640

Official record on ClinicalTrials.gov — NCT00063063

Locations in the U.S.

Alabama	University of Alabama at Birmingham, Birmingham
California	Stanford University, Palo Alto Sharp Mary Birch Hospital for Women & Newborns, San Diego
Georgia	Emory University, Atlanta
Illinois	Northwestern Lurie Children's Hospital of Chicago, Chicago (Not yet recruiting)
Iowa	University of Iowa, Iowa City
Mississippi	University of Mississippi Medical Center - Children's of Mississippi, Jackson (Not yet recruiting)
New Mexico	University of New Mexico, Albuquerque
North Carolina	Duke University, Durham
Ohio	Cincinnati Children's Medical Center, Cincinnati Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland
Pennsylvania	Univeristy of Pennsylvania, Philadelphia
Texas	University of Texas Southwestern Medical Center at Dallas, Dallas University of Texas Health Science Center at Houston, Houston
Utah	University of Utah, Salt Lake City

Conditions

Premature Birth

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.