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Clinical Research in ALS Study

RecruitingObservational studyHealthy volunteers welcome

Clinical Research in Amyotrophic Lateral Sclerosis

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria

Inclusion Criteria:

1. At least 18 years of age.
2. Member of at least one of the following categories:

   1. Individuals affected with ALS or a related neurodegenerative disease (sporadic or familial)
   2. Unaffected individuals from fALS pedigrees, including pre-symptomatic individuals at genetic risk for ALS or individuals from pedigrees of ALS related diseases.
   3. Healthy controls
3. Able and willing to comply with relevant procedures.

Exclusion Criteria:

1\. Subject has a condition or is in a situation which, in the PI's opinion, could confound the study finding or may interfere significantly with the individual's participation and compliance with the study protocol -- including but not limited to neurological, psychological and/or medical conditions (e.g., multiple sclerosis, neuropathy, myelopathy).

About the study

CRiALS is an umbrella protocol through which people are recruited to participate in a range of research studies being conducted by the ALS Research Collaboration (ARC).

Sponsor: University of Miami · Participants: 10,000 · Started: 2005-02

Contact the study team

Anne-Laure Grignon, MD · Phone: 888-413-9315

Official record on ClinicalTrials.gov — NCT00136500

Locations in the U.S.

Florida

University of Miami, Miami

Conditions

Amyotrophic Lateral Sclerosis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.