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BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Who can join

Ages 18 to 80 · All sexes

Inclusion Criteria:

* Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis or other motor neuron disorders
* Complete or incomplete tetraplegia (quadriplegia)
* Must live within a three-hour drive of the Study site
* (There are additional inclusion criteria)

Exclusion Criteria:

* Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses
* Chronic oral or intravenous steroids or immunosuppressive therapy
* Other serious disease or disorder that could seriously affect ability to participate in the study
* (There are additional exclusion criteria)

About the study

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.

What is being tested

• Placement of the BrainGate2 sensor(s) into the motor-related cortex (device)

Sponsor: Leigh R. Hochberg, MD, PhD. · Participants: 27 · Started: 2009-05

Contact the study team

• Leigh R Hochberg, M.D., Ph.D. · Phone: 617-724-9247

Official record on ClinicalTrials.gov — NCT00912041

Locations in the U.S.

Conditions

• Quadriplegia
• Spinal Cord Injuries
• Amyotrophic Lateral Sclerosis
• Brain Stem Infarctions
• Muscular Dystrophy

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.