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MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine

MRI-Guided Cryoablation of Head, Neck and Spine Nerves and Facets Using the Advanced Multimodality Image Guided Operating(AMIGO) Suite

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Participants must be willing and able to sign a written informed consent document.
* Patients must have facet joint disease or pain due to a damaged or compressed nerve that would benefit from a minimally invasive image-guided procedure (i.e., adjacent to critical structures, better visualized under 3 Tesla MRI than CT)
* Subjects must be able to adhere to the visit schedules and attend pre and post imaging.
* Participants must be at least 18 years of age
* Participants must have an estimated life expectancy of \>8 weeks in the opinion of the clinician.

  * Patients with radiculopathy must have the cause of pain confirmed by a nerve block within 3 months prior to ablation

Exclusion Criteria:

* Contraindications to MRI and Gadolinium- (i.e. estimated Glomerular Filtration Rate \<60ml/min, metal clips)
* Pregnant or breastfeeding woman are excluded from this research.

About the study

The objective of this study is to provide pain relief to patients with facet joint disease or head and neck pain related to compression of a nerve root. The goal is to provide palliative care with superior efficacy and longer relief compared to current methods.

What is being tested

• Cryoablation under image guidance (procedure)
• MRI Seednet Cryotherapy System (Galil Medical) (device)

Sponsor: Brigham and Women's Hospital · Participants: 50 · Started: 2013-05

Contact the study team

• Thomas Lee, MD · Phone: (617) 732-7260
• Danielle Chamberlain, BS, RT(R) · Phone: 617-525-8596

Official record on ClinicalTrials.gov — NCT01788410

Locations in the U.S.

Conditions

• Nerve Pain (Neuralgia)
• Pain

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.