๐Ÿ”Ž Trials Near Me

Home โ€บ Pain

Pain clinical trials recruiting in the U.S.

203 studies for Pain are recruiting participants at sites across the United States.

Pain is a feeling triggered in the nervous system. You may feel it as a prick, tingle, sting, burn, or ache. Read about the causes and what can help.

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Recently updated studies

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 13, 2026 ยท NCT07210515

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Nov 13, 2026 ยท NCT01719055

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

Recruiting
Ages 12 to 22 ยท All sexes ยท Updated Nov 13, 2026 ยท NCT06232304

Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery

Recruiting
Ages 18 and older ยท Women ยท Updated Nov 12, 2026 ยท NCT07185425

Neural and Psychological Mechanisms of Pain Perception

RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT02446262

Evaluating Intranasal Oxytocin (TNX-1900) for Pain Relief and Recovery After Pituitary Surgery

RecruitingPhase 2
Ages 30 to 75 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07730294

Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery

RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT06767566

The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery

RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Nov 2, 2026 ยท NCT07224711

Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy

Recruiting
Ages 18 to 85 ยท All sexes ยท Updated Oct 30, 2026 ยท NCT06965452

VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain

Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 29, 2026 ยท NCT06336447

Dry Needling in Multiple Sclerosis

Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT07615725

A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain

RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated Oct 23, 2026 ยท NCT07874620

Behavioral Economic & Staffing Strategies in the ICU

Recruiting
Ages 19 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT06184945

An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin

RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Oct 23, 2026 ยท NCT07845071

This Study is Comparing Pain Outcomes After Urethral Bulking When Participants Are Randomized to Two Different Pain Medication Regimens.

RecruitingPhase 4
Ages 18 and older ยท Women ยท Updated Oct 22, 2026 ยท NCT07889687

Acute Cryotherapy on Musculoskeletal Function and Biomarkers

RecruitingHealthy volunteers welcome
Ages 18 to 30 ยท All sexes ยท Updated Oct 22, 2026 ยท NCT07211412

Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine

RecruitingEarly phase 1
Ages 18 to 70 ยท All sexes ยท Updated Oct 21, 2026 ยท NCT07886606

Morphine or Ketamine for Analgesia

RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Oct 20, 2026 ยท NCT06835504

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

RecruitingHealthy volunteers welcome
Ages 18 to 60 ยท All sexes ยท Updated Oct 20, 2026 ยท NCT03258580

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 16, 2026 ยท NCT05492188

Anesthetics and Analgesics in Children

RecruitingObservational study
6 Months โ€“ 17 Years ยท All sexes ยท Updated Oct 16, 2026 ยท NCT03427736

Phase 3, Open-Label Extension Study of AMBTX-01 (Neridronate) for Complex Regional Pain Syndrome Type 1

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 16, 2026 ยท NCT07857733

Options for Pain Management Using Nonpharmacological Strategies

Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 15, 2026 ยท NCT05563792

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.