๐Ÿ”Ž Trials Near Me

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Pain clinical trials recruiting in the U.S.

205 studies for Pain are recruiting participants at sites across the United States.

Pain is a feeling triggered in the nervous system. You may feel it as a prick, tingle, sting, burn, or ache. Read about the causes and what can help.

Cities with the most studies

By state

Recently updated studies

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

RecruitingHealthy volunteers welcome
Ages 18 to 60 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT03258580

An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin

RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07845071

Chronic Postsurgical Pain

RecruitingObservational study
Ages 5 to 17 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT05764681

Neural and Psychological Mechanisms of Pain Perception

RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT02446262

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

RecruitingPhase 2
Ages 18 and older ยท Women ยท Updated Sep 22, 2026 ยท NCT06728579

Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort

RecruitingEarly phase 1
Ages 18 to 50 ยท All sexes ยท Updated Sep 18, 2026 ยท NCT06472622

Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

Recruiting
Ages 18 and older ยท Women ยท Updated Sep 18, 2026 ยท NCT06991075

Impact of Art Therapy on Self-Reported Pain and Anxiety Scores of Patients Waiting to Be Seen in the Emergency Department

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 17, 2026 ยท NCT05540106

State-dependent Interoception, Value-based Decision-making, and Introspection

RecruitingHealthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT05666726

Transcutaneous Vagus Nerve Stimulation in SLE

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 17, 2026 ยท NCT06987565

Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children

Recruiting
Ages 7 to 12 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT07222943

Clinical and Scientific Assessment of Pain and Painful Disorders

RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 120 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT02707029

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED

RecruitingPhase 4
Ages 18 to 120 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06364540

Transdiagnostic Cognitive Biomarkers

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT04864080

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06471075

Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients

Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT06009159

Post-stroke Pain tAN-fMRI

Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07144436

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 11, 2026 ยท NCT01719055

Massage, Oncology, Pain, Anxiety, Feasibility

Recruiting
Ages 18 to 85 ยท Women ยท Updated Sep 10, 2026 ยท NCT07502157

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 10, 2026 ยท NCT07210515

Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection

Recruiting
Ages 40 and older ยท All sexes ยท Updated Sep 4, 2026 ยท NCT07804446

High Potency Cannabis: Acute and Protracted Effects

RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 55 ยท All sexes ยท Updated Sep 4, 2026 ยท NCT06859723

Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy

Recruiting
Ages 18 to 85 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT06965452

MDMA-assisted Therapy for Fibromyalgia

RecruitingEarly phase 1
Ages 21 to 65 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT06066853

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.