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Type 1 Diabetes Extension Study

RecruitingObservational study

Who can join

Ages 8 to 35 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Prior participant in an Immune Tolerance Network (ITN) executive committee approved T1DM study.
* Ability to sign informed consent/assent (as applicable for children).

Exclusion Criteria:

* Any medical condition that in the opinion of the principal investigator would interfere with safe completion of the trial; or
* Inability to comply with the study visit schedule and required assessments.

About the study

This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodulatory agents (T1DM, T1D).

This observational study will:

* follow participants to determine how long they continue to produce insulin, and * will also assess how changes in the immune system over time relate to the ability to produce insulin.

This information could help design better therapies for type 1 diabetes in the future.

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) · Participants: 111 · Started: Jun 8, 2016

Contact the study team

Official record on ClinicalTrials.gov — NCT02734277

Locations in the U.S.

CaliforniaUCSF School of Medicine, San Francisco
Stanford University, Stanford
ColoradoUniversity of Colorado School of Medicine: Barbara Davis Center for Diabetes, Aurora
IndianaIndiana University Riley Hospital for Children, Indianapolis
IowaUniversity of Iowa Health Care Division of Pediatric Endocrinology, Iowa City
MassachusettsJoslin Diabetes Center, Boston
MinnesotaUniversity of Minnesota, Minneapolis
WashingtonBenaroya Research Institute, Seattle

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.