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Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

Pilot Investigation of Using Electrocorticogram (ECoG) in Predicting Eloquent Cortex and Post-Operative Functional Outcomes in Patients With Brain Tumors

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Patients undergoing a tumor resection at the University of Texas M. D. Anderson Cancer Center for a newly diagnosed as well as recurrent primary or metastatic brain tumor located in or adjacent to motor and/or speech brain areas
* Patients \>= 18 years of age
* Signed informed consent

Exclusion Criteria:

* Patients with significant neurological motor deficits of the upper extremities, and/or speech deficits, which would preclude them from performing the while awake intra-operative tasks at the discretion of the principal investigator (PI)
* Patients who have impaired vision and/or hearing and whose performance could affect the study will be excluded at the discretion of the PI

About the study

This pilot clinical trial studies how well electrocorticography works in mapping functional brain areas during surgery in patients with brain tumors. Using a larger than the standard mapping grid currently used during brain tumor surgery or a high-definition grid for electrocorticogram brain mapping may help doctors to better identify which areas of the brain are active during specific limb movement and speech during surgery in patients with brain tumors.

What is being tested

• Direct Electrocortical Stimulation (procedure)
• Electrocorticography (other)

Sponsor: M.D. Anderson Cancer Center · Participants: 75 · Started: Jul 22, 2016

Contact the study team

• Sujit Prabhu, MD · Phone: 713-792-2400

Official record on ClinicalTrials.gov — NCT02754544

Locations in the U.S.

Conditions

• Brain Tumors

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.