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Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
Protocol for Immunology Specimen Collection From Cancer Patients, Patients With Hematologic Diagnoses, and Healthy Normal Controls
Who can join
Ages 19 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * All patients known to have cancer, an immune-mediated hematologic diagnosis, or a healthy normal volunteer * Definition of immune-mediated hematologic diagnosis: diagnoses for which immune dysfunction and/or immune system directed therapy (eg. aplastic anemia, autoimmune hemolytic anemia, immune thrombocytopenic purpura \[ITP\], etc.) are involved * Definition of healthy normal volunteer: persons lacking diagnoses of any type of cancer, diabetes, cardiovascular diseases, non-hematologic autoimmune disease (eg. systemic lupus erythematosus \[SLE\], rheumatoid arthritis \[RA\], Crohn's disease) and not taking any immunosuppressive medications * Patients must have been seen in the Norris Hospital and outpatient clinics, or the Los Angeles County (LAC)-University of Southern California (USC) Medical Center or outpatient clinics; healthy volunteers can be recruited without any physician visit appointments since their labs are strictly for clinical research and not for personal health issues unrelated to the project Exclusion Criteria: * Unable to give informed consent to specimen collection * Known human immunodeficiency virus (HIV) positive status * Persons taking any type of immunosuppressive medication are excluded from participating as healthy normal volunteers * Any patient for whom specimen collection is judged to be unsafe (for example, for patients unable to establish venous access)
About the study
This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.
What is being tested
- Biospecimen Collection (procedure)
- Laboratory Biomarker Analysis (other)
- Questionnaire Administration (other)
Sponsor: University of Southern California · Participants: 625 · Started: Apr 12, 2017
Contact the study team
- Arta Zenunovic · Phone: 323-442 7828
Official record on ClinicalTrials.gov — NCT03207854
Locations in the U.S.
| California | USC / Norris Comprehensive Cancer Center, Los Angeles |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.