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Mucosal and Microbiota Changes During Acute Campylobacteriosis

Who can join

Ages 18 to 80 · All sexes

Inclusion Criteria:

* No abdominal surgery (except appendectomy and cholecystectomy)
* Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter

Exclusion Criteria:

* History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease.
* History of gastroenteritis in six months prior to Campylobacter enteritis
* Pregnancy

About the study

Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future.

Sponsor: Mayo Clinic · Participants: 150 · Started: Oct 31, 2014

Contact the study team

• Margaret K Breen-Lyles, BS · Phone: 507-255-3520

Official record on ClinicalTrials.gov — NCT03223077

Locations in the U.S.

Conditions

• Irritable Bowel Syndrome

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.