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A Study Comparing Quality of Life in Patients With Lymphedema Who Undergo Surgical Treatment Versus Non-Surgical Management

A Prospective Study Comparing Quality of Life in Patients With Lymphedema Who Undergo Surgical Treatment Versus Non-Surgical Management

Who can join

Ages 18 to 80 · All sexes

Inclusion Criteria:

* Patients aged 18-80 years
* Primary and secondary lymphedema of the upper or lower extremity
* International Society of Lymphology (ISL) Stage 1, 2, or 3 lymphedema
* Proficiency in English language

Exclusion Criteria:

* Patients with clotting disorders, venous insufficiency, end-stage lymphedema unless they are on the non-surgical arm.
* Additionally, if the patient refuses to complete questionnaires, the patient will be excluded from the study and replaced at the discretion of the principal or co-principal investigator.

About the study

This study is being done to see the long-term results for patients who choose to have surgery for lymphedema (with the vascularized lymph node transfer), compared to patients who choose not to have surgery.

What is being tested

• Quality of Life Assessments (behavioral)

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 600 · Started: Aug 9, 2017

Contact the study team

• Babak Mahrara, MD · Phone: 646-608-8085
• Andrea Barrio, MD · Phone: 646-888-5118

Official record on ClinicalTrials.gov — NCT03248310

Locations in the U.S.

Conditions

• Lymphedema

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.