Anesthetics and Analgesics in Children
RecruitingObservational study
Pharmacokinetics of Anesthetics and Analgesics in Children and Adolescent
Who can join
Ages 0 to 17 · All sexes
Full eligibility criteria
Inclusion Criteria: 1. 0 to \<18 years of age at time of enrollment (must see applicable appendix for details as not all appendices enroll across the entire age range) 2. Parent and/or participant (if applicable) is able to understand the consent process and provides informed consent and HIPAA Authorization (if applicable) 3. Participant provides assent as required by the institutional review board (IRB) or research ethics board (REB) 4. Receiving one or more drugs of interest (DOI) per local standard of care 5. Meeting DOI-specific inclusion criteria (See Appendices) Exclusion Criteria: 1. Known pregnancy 2. Extracorporeal life support (i.e., ECMO, dialysis, ventricular assist device) 3. Any condition which would make the participant, in the opinion of the investigator, unsuitable for the study
About the study
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
What is being tested
- Ketorolac Tromethamine (drug)
- Hydromorphone (drug)
- Ketamine (drug)
- Oxycodone (drug)
- Morphine (drug)
Sponsor: Chi Dang Hornik · Participants: 551 · Started: Dec 13, 2018
Contact the study team
- Kady-Ann Steen-Burrell, PhD · Phone: 919-530-9711
- Cheryl Alderman · Phone: 919-668-8349
Official record on ClinicalTrials.gov — NCT03427736
Locations in the U.S.
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.