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Anesthetics and Analgesics in Children

RecruitingObservational study

Pharmacokinetics of Anesthetics and Analgesics in Children and Adolescent

Who can join

Ages 0 to 17 · All sexes

Full eligibility criteria
Inclusion Criteria:

1. 0 to \<18 years of age at time of enrollment (must see applicable appendix for details as not all appendices enroll across the entire age range)
2. Parent and/or participant (if applicable) is able to understand the consent process and provides informed consent and HIPAA Authorization (if applicable)
3. Participant provides assent as required by the institutional review board (IRB) or research ethics board (REB)
4. Receiving one or more drugs of interest (DOI) per local standard of care
5. Meeting DOI-specific inclusion criteria (See Appendices)

Exclusion Criteria:

1. Known pregnancy
2. Extracorporeal life support (i.e., ECMO, dialysis, ventricular assist device)
3. Any condition which would make the participant, in the opinion of the investigator, unsuitable for the study

About the study

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

What is being tested

Sponsor: Chi Dang Hornik · Participants: 551 · Started: Dec 13, 2018

Contact the study team

Official record on ClinicalTrials.gov — NCT03427736

Locations in the U.S.

CaliforniaLucile Packard Children's Hospital, Stanford
IllinoisAnn and Robert H. Lurie Childrens Hospital of Chicago, Chicago
North CarolinaDuke University Medical Center, Durham
South CarolinaMedical University of South Carolina, Charleston

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.